CD151 Antibody (PE)
429€ (100 tests)
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Name
CD151 Antibody (PE)
Category
Primary Antibodies
Provider
Abbexa
Reference
abx140520
Tested Applications
FCM
Description
CD151 Antibody (PE) is a Mouse Monoclonal against CD151.
Documentos del producto
Instrucciones
Data sheet
Especificaciones del producto
| Category | Primary Antibodies |
| Immunogen Target | Target: CD151 Immunogen: Human epidermoid carcinoma cell line Hep-3. |
| Host | Mouse |
| Reactivity | Human |
| Detection Method | Laser Line: 550 Excitation/Emission: 565/575 |
| Recommended Dilution | FCM: 10 µl/100 µl of whole blood or 106 cells. Optimal dilutions/concentrations should be determined by the end user. |
| Clonality | Monoclonal |
| Conjugation | PE |
| Isotype | IgG1 Kappa |
| Clone ID | A480 |
| Size 1 | 100 tests |
| Tested Applications | FCM |
| Buffer | Stabilizing PBS solution containing 15 mM sodium azide. |
| Availability | Shipped within 5-12 working days. |
| Storage | Store in the dark at 2-8°C. Avoid exposure to light. Do not freeze. |
| Dry Ice | No |
| UniProt ID | P48509 |
| Gene ID | 977 |
| Alias | Raph blood group,EBS7,GP27,MER2,RAPH,SFA1,PETA-3,TSPAN24,Membrane glycoprotein SFA-1,Platelet-endothelial tetraspan antigen 3,Tetraspanin-24 |
| Background | Antibody anti-CD151 |
| Status | RUO |
| Note | THIS PRODUCT IS FOR RESEARCH USE ONLY. NOT FOR USE IN DIAGNOSTIC, THERAPEUTIC OR COSMETIC PROCEDURES. NOT FOR HUMAN OR ANIMAL CONSUMPTION. |
Background
CD151 is a cell-surface protein belonging to the tetraspanin family, a group of transmembrane proteins involved in cell signaling, adhesion, and migration. This protein, encoded by the CD151 gene, is expressed on a wide range of cell types, including epithelial cells, endothelial cells, platelets, and certain hematopoietic cells. CD151 is known to interact with various integrins—primarily integrins α3β1, α6β1, and α6β4—which are crucial for cellular adhesion to the extracellular matrix (ECM) and in forming stable cellular junctions. CD151 is a key player in numerous physiological processes, including wound healing, angiogenesis, hemostasis, and immune responses. Additionally, this protein has been implicated in various diseases, notably cancer metastasis, kidney disease, and platelet-related disorders. Given its integral role in cellular adhesion and signaling, CD151 is considered a therapeutic target in certain diseases.
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