CCR4-NOT Transcription Complex Subunit 9 (CNOT9) Antibody

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Description
CCR4-NOT Transcription Complex Subunit 9 (CNOT9) Antibody is a Rabbit polyclonal antibody for the detection of Human CCR4-NOT Transcription Complex Subunit 9 (CNOT9).
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Product specifications
Category | Primary Antibodies |
Immunogen Target | CCR4-NOT Transcription Complex Subunit 9 (CNOT9) |
Host | Rabbit |
Reactivity | Human |
Recommended Dilution | Optimal dilutions/concentrations should be determined by the end user. |
Clonality | Polyclonal |
Conjugation | Unconjugated |
Isotype | IgG |
Size 1 | 50 µg |
Size 2 | 100 µg |
Form | Liquid |
Tested Applications | ELISA, WB, IHC |
Buffer | 0.01 M PBS, pH 7.4, 50% glycerol, 0.05% Proclin-300. |
Availability | Shipped within 5-12 working days. |
Storage | Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles. |
Dry Ice | No |
UniProt ID | Q92600 |
Gene ID | 9125 |
NCBI Accession | NP_001258563.1 |
Background | Antibody anti-CNOT9 |
Status | RUO |
Descripción
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Component of the CCR4-NOT complex which is one of the major cellular mRNA deadenylases and is linked to various cellular processes including bulk mRNA degradation, miRNA-mediated repression, translational repression during translational initiation and general transcription regulation. Additional complex functions may be a consequence of its influence on mRNA expression. Involved in down-regulation of MYB-and JUN-dependent transcription. May play a role in cell differentiation(By similarity). Can bind oligonucleotides, such as poly-G, poly-C or poly-T(in vitro), but the physiological relevance of this is not certain. Does not bind poly-A. Enhances ligand-dependent transcriptional activity of nuclear hormone receptors, including RARA, expect ESR1-mediated transcription that is not only slightly increased, if at all.
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