CCR4-NOT Transcription Complex Subunit 2 (CNOT2) Antibody
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Description
CCR4-NOT Transcription Complex Subunit 2 (CNOT2) Antibody is a Rabbit polyclonal antibody for the detection of Human CCR4-NOT Transcription Complex Subunit 2 (CNOT2).
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Product specifications
| Category | Primary Antibodies |
| Immunogen Target | CCR4-NOT Transcription Complex Subunit 2 (CNOT2) |
| Host | Rabbit |
| Reactivity | Human |
| Recommended Dilution | Optimal dilutions/concentrations should be determined by the end user. |
| Clonality | Polyclonal |
| Conjugation | Unconjugated |
| Isotype | IgG |
| Size 1 | 50 µg |
| Size 2 | 100 µg |
| Form | Liquid |
| Tested Applications | ELISA, WB, IHC |
| Buffer | 0.01 M PBS, pH 7.4, 50% glycerol, 0.05% Proclin-300. |
| Availability | Shipped within 5-12 working days. |
| Storage | Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles. |
| Dry Ice | No |
| UniProt ID | Q9NZN8 |
| Gene ID | 4848 |
| NCBI Accession | NP_001186231.1 |
| Background | Antibody anti-CNOT2 |
| Status | RUO |
Descripción
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Component of the CCR4-NOT complex which is one of the major cellular mRNA deadenylases and is linked to various cellular processes including bulk mRNA degradation, miRNA-mediated repression, translational repression during translational initiation and general transcription regulation. Additional complex functions may be a consequence of its influence on mRNA expression. Required for the CCR4-NOT complex structural integrity. Can repress transcription and may link the CCR4-NOT complex to transcriptional regulation; the repressive function may specificly involve the N-Cor repressor complex containing HDAC3, NCOR1 and NCOR2. Involved in the maintenance of emryonic stem(ES) cell identity.
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