Catechol O-Methyltransferase (COMT) Antibody
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Description
Catechol O-Methyltransferase (COMT) Antibody is a Rabbit polyclonal antibody for the detection of Human Catechol O-Methyltransferase (COMT).
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Product specifications
| Category | Primary Antibodies |
| Immunogen Target | Catechol O-Methyltransferase (COMT) |
| Host | Rabbit |
| Reactivity | Human |
| Recommended Dilution | Optimal dilutions/concentrations should be determined by the end user. |
| Clonality | Polyclonal |
| Conjugation | Unconjugated |
| Isotype | IgG |
| Size 1 | 50 µg |
| Size 2 | 100 µg |
| Form | Liquid |
| Tested Applications | ELISA, WB, IHC |
| Buffer | 0.01 M PBS, pH 7.4, 50% glycerol, 0.05% Proclin-300. |
| Availability | Shipped within 5-12 working days. |
| Storage | Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles. |
| Dry Ice | No |
| UniProt ID | P21964 |
| Gene ID | 1312 |
| NCBI Accession | NP_000745.1 |
| Background | Antibody anti-COMT |
| Status | RUO |
Descripción
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Human COMT (Catechol O-methyltransferase) ELISA Kit
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COMT antibody
Catechol-O-methyltransferase catalyzes the transfer of a methyl group from S-adenosylmethionine to catecholamines, including the neurotransmitters dopamine, epinephrine, and norepinephrine. This O-methylation results in one of the major degradative pathways of the catecholamine transmitters. In addition to its role in the metabolism of endogenous substances, COMT is important in the metabolism of catechol drugs used in the treatment of hypertension, asthma, and Parkinson disease. COMT is found in two forms in tissues, a soluble form (S-COMT) and a membrane-bound form (MB-COMT). The differences between S-COMT and MB-COMT reside within the N-termini. Several transcript variants are formed through the use of alternative translation initiation sites and promoters.
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