Caspase Recruitment Domain Family Member 6 (CARD6) Antibody
442€ (200 µl)
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935106861
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name
Caspase Recruitment Domain Family Member 6 (CARD6) Antibody
category
Primary Antibodies
provider
Abbexa
reference
abx432448
tested applications
P-ELISA, IHC
Description
CARD6 Antibody is a Goat Polyclonal antibody against CARD6.
Documents del producto
Instrucciones
Data sheet
Product specifications
| Category | Primary Antibodies |
| Immunogen Target | Target: Caspase Recruitment Domain Family Member 6 (CARD6) Immunogen: abx269334 - N-Terminus: ATESTPSEIIERER-C |
| Host | Goat |
| Reactivity | Human |
| Assay Type | Concentration: 0.5 mg/ml |
| Recommended Dilution | P-ELISA: 1/32000. Optimal dilutions/concentrations should be determined by the end user. |
| Clonality | Polyclonal |
| Conjugation | Unconjugated |
| Isotype | IgG |
| Purification | Purified from goat serum by ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide. |
| Size 1 | 200 µl |
| Form | Liquid |
| Tested Applications | P-ELISA, IHC |
| Buffer | Tris saline, pH 7.3, containing 0.02% sodium azide and 0.5% bovine serum albumin. |
| Availability | Shipped within 5-10 working days. |
| Storage | Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles. |
| Dry Ice | No |
| Gene ID | 84674 |
| NCBI Accession | NP_115976.2 |
| Alias | CINCIN1 |
| Background | Antibody anti-CARD6 |
| Status | RUO |
| Note | THIS PRODUCT IS FOR RESEARCH USE ONLY. NOT FOR USE IN DIAGNOSTIC, THERAPEUTIC OR COSMETIC PROCEDURES. NOT FOR HUMAN OR ANIMAL CONSUMPTION. |
Descripción
CARD6 is part of the caspase recruitment domain family of proteins and is involved in the regulation of immune cell signaling, particularly in response to stress and inflammation. CARD6 is expressed in various tissues, including immune cells, and is believed to play a role in controlling NF-κB signaling pathways. While it shares the CARD domain with other family members like CARD9 and CARD8, CARD6 has distinct functions, including its involvement in apoptosis and inflammatory responses. It can modulate both pro-inflammatory and anti-inflammatory signaling, making it an important protein in the balance of immune activation. In certain conditions, such as chronic inflammatory diseases, the activity of CARD6 can become dysregulated, contributing to excessive inflammation. Further understanding of CARD6’s role in immune signaling may provide insights into therapeutic strategies for diseases involving chronic inflammation and autoimmune disorders.
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