Caspase Recruitment Domain-Containing Protein 14 (CARD14) Antibody (HRP)
169€ (20 µg)
Por favor contáctenos para obtener información detallada sobre el precio y disponibilidad.
935106861
info@markelab.com
name
Caspase Recruitment Domain-Containing Protein 14 (CARD14) Antibody (HRP)
category
Primary Antibodies
provider
Abbexa
reference
abx334989
tested applications
ELISA
Description
CARD14 Antibody (HRP) is a Rabbit Polyclonal against CARD14.
Documents del producto
Instrucciones
Data sheet
Product specifications
| Category | Primary Antibodies |
| Immunogen Target | Caspase Recruitment Domain-Containing Protein 14 (CARD14) |
| Host | Rabbit |
| Reactivity | Human |
| Recommended Dilution | Optimal dilutions/concentrations should be determined by the end user. |
| Clonality | Polyclonal |
| Conjugation | HRP |
| Isotype | IgG |
| Purity | > 95% |
| Purification | Purified by Protein G. |
| Size 1 | 20 µg |
| Size 2 | 50 µg |
| Size 3 | 100 µg |
| Size 4 | 200 µg |
| Size 5 | 1 mg |
| Form | Liquid |
| Tested Applications | ELISA |
| Buffer | 0.01 M PBS, pH 7.4, 0.03% Proclin-300 and 50% Glycerol. |
| Availability | Shipped within 5-10 working days. |
| Storage | Aliquot and store at -20°C. Avoid exposure to light. Avoid repeated freeze/thaw cycles. |
| Dry Ice | No |
| UniProt ID | Q9BXL6 |
| Gene ID | 79092 |
| OMIM | 173200 |
| Alias | CARD14,BIMP2, CARMA2, PRP, PSORS2, PSS1,CARD-containing MAGUK protein 2 |
| Background | Antibody anti-CARD14 |
| Status | RUO |
Descripción
CARD14, also known as CARMA2 (Caspase Recruitment Domain-Containing Membrane-Associated Protein 2), is a protein that plays an important role in immune cell signaling, especially in the activation of NF-κB and other inflammatory pathways. It acts as an adaptor protein in the NF-κB signaling cascade, which is crucial for the immune response to pathogens. CARD14 is involved in various immune system functions, including the regulation of cytokine production and the activation of immune cells in response to infection. Recent studies have shown that CARD14 mutations are associated with psoriasis, an autoimmune skin disorder, suggesting that its regulation of immune responses is vital for maintaining immune system balance. Inappropriate activation or suppression of CARD14 may lead to the development of chronic inflammatory diseases, making it a potential target for therapeutic interventions in conditions such as psoriasis and other immune-related diseases.
Related Products
CARD14 antibody
Plays a role in signaling mediated by TRAF2, TRAF3 and TRAF6 and protects cells against apoptosis. Activates NF-kappa-B via BCL10 and IKK. Stimulates the phosphorylation of BCL10.
Ver Producto
Recombinant Human CARD14
Ver Producto
Caspase Recruitment Domain-Containing Protein 14 (CARD14) Antibody
Caspase Recruitment Domain-Containing Protein 14 (CARD14) Antibody is a Rabbit Polyclonal antibody against Caspase Recruitment Domain-Containing Protein 14 (CARD14).
Ver Producto