Cardiotrophin-Like Cytokine Factor 1 Protein
Por favor contáctenos para obtener información detallada sobre el precio y disponibilidad.
Description
Cardiotrophin-Like Cytokine Factor 1 Protein is a recombinant cytokine.
Documents del producto
Product specifications
| Category | Proteins and Peptides |
| Immunogen Target | CLCF1 |
| Origin | Human |
| Conjugation | Unconjugated |
| Expression | Recombinant |
| Purity | > 90% (SDS-PAGE) |
| Size 1 | 5 µg |
| Size 2 | 20 µg |
| Size 3 | 1 mg |
| Form | Liquid |
| Tested Applications | SDS-PAGE |
| Availability | Shipped within 5-10 working days. |
| Dry Ice | No |
| UniProt ID | Q9UBD9 |
| Background | Protein CLCF1 |
| Status | RUO |
| Note | This product is for research use only. Not for human consumption, cosmetic, therapeutic or diagnostic use. |
Descripción
Related Products
Human CLCF1 (Cardiotrophin-like cytokine factor 1) ELISA Kit
Ver Producto
Mouse CLCF1 (Cardiotrophin Like Cytokine Factor 1) ELISA Kit
Ver Producto
Cardiotrophin Like Cytokine Factor 1 (CLCF1) Antibody
This gene is a member of the glycoprotein (gp) 130 cytokine family and encodes cardiotrophin-like cytokine factor 1 (CLCF1). CLCF1 forms a heterodimer complex with cytokine receptor-like factor 1 (CRLF1). This dimer competes with ciliary neurotrophic factor (CNTF) for binding to the ciliary neurotrophic factor receptor (CNTFR) complex, and activates the Jak-STAT signaling cascade. CLCF1 can be actively secreted from cells by forming a complex with soluble type I CRLF1 or soluble CNTFR. CLCF1 is a potent neurotrophic factor, B-cell stimulatory agent and neuroendocrine modulator of pituitary corticotroph function. Defects in CLCF1 cause cold-induced sweating syndrome 2 (CISS2). This syndrome is characterized by a profuse sweating after exposure to cold as well as congenital physical abnormalities of the head and spine. Alternative splicing results in multiple transcript variants encoding distinct isoforms.
Ver Producto