Carcinoembryonic Antigen Related Cell Adhesion Molecule 6 (CEACAM6) Antibody (PE)
429€ (100 tests)
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935106861
info@markelab.com
name
Carcinoembryonic Antigen Related Cell Adhesion Molecule 6 (CEACAM6) Antibody (PE)
category
Primary Antibodies
provider
Abbexa
reference
abx347176
tested applications
FCM
Description
Carcinoembryonic Antigen Related Cell Adhesion Molecule 6 (CEACAM6) Antibody (PE) is a mouse monoclonal antibody against Carcinoembryonic Antigen Related Cell Adhesion Molecule 6 (CEACAM6).
Documents del producto
Instrucciones
Data sheet
Product specifications
| Category | Primary Antibodies |
| Immunogen Target | Carcinoembryonic Antigen Related Cell Adhesion Molecule 6 (CEACAM6) |
| Host | Mouse |
| Reactivity | Human |
| Recommended Dilution | FCM: 10 μl/100 μl of whole blood or 106 cells. Optimal dilutions/concentrations should be determined by the end user. |
| Clonality | Monoclonal |
| Conjugation | PE |
| Isotype | IgG1 Kappa |
| Clone ID | G810 |
| Size 1 | 100 tests |
| Tested Applications | FCM |
| Buffer | Stabilizing PBS solution containing 15 mM sodium azide. |
| Availability | Shipped within 5-12 working days. |
| Storage | Store in the dark at 2-8°C. Avoid exposure to light. Do not freeze. |
| Dry Ice | No |
| UniProt ID | P40199 |
| Gene ID | 4680 |
| OMIM | 163980 |
| Alias | NCA,CEAL,CD66c,NCA-50/90,Carcinoembryonic antigen-related cell adhesion molecule 6 |
| Background | Antibody anti-CEACAM6 |
| Status | RUO |
Descripción
CEACAM6, also known as CD66c (Cluster of Differentiation 66c), is a member of the carcinoembryonic antigen-related cell adhesion molecules (CEACAMs), which belong to the larger immunoglobulin superfamily (IgSF). CEACAM6 is a glycoprotein primarily involved in intercellular adhesion, immune response modulation, and tumor progression. It is expressed on the surface of various cell types, particularly epithelial cells, granulocytes, and certain cancer cells. CEACAM6, like other CEACAM family members, plays a key role in cellular interactions and communication. In addition to its normal physiological roles in cell adhesion, CEACAM6 is implicated in tumorigenesis, especially in cancers like colorectal, pancreatic, lung, and breast cancer. CEACAM6 is often overexpressed in these malignancies, contributing to tumor growth, metastasis, and resistance to apoptosis. Its expression in the immune system and epithelial cells also means it has important functions in immune modulation and maintaining the integrity of epithelial barriers.
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