Carcinoembryonic Antigen Related Cell Adhesion Molecule 6 (CEACAM6) Antibody (PE)
637€ (100 tests)
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935106861
info@markelab.com
name
Carcinoembryonic Antigen Related Cell Adhesion Molecule 6 (CEACAM6) Antibody (PE)
category
Primary Antibodies
provider
Abbexa
reference
abx270822
tested applications
FCM
Description
Carcinoembryonic Antigen Related Cell Adhesion Molecule 6 (CEACAM6) Antibody (PE) is a Rabbit Polyclonal Antibody conjugated to PE against Carcinoembryonic Antigen Related Cell Adhesion Molecule 6 (CEACAM6) for use in flow cytometry.
Documents del producto
Instrucciones
Data sheet
Product specifications
| Category | Primary Antibodies |
| Immunogen Target | Carcinoembryonic Antigen Related Cell Adhesion Molecule 6 (CEACAM6) |
| Host | Rabbit |
| Reactivity | Human |
| Recommended Dilution | FCM: 1-5 µl/106 cells. Optimal dilutions/concentrations should be determined by the end user. |
| Clonality | Polyclonal |
| Conjugation | PE |
| Isotype | IgG |
| Purification | Purified by antigen-specific affinity chromatography. |
| Size 1 | 100 tests |
| Size 2 | 200 tests |
| Size 3 | 500 tests |
| Form | Liquid |
| Tested Applications | FCM |
| Buffer | 0.01 M PBS, pH 7.4, containing 0.05% Proclin-300, 50% glycerol. |
| Availability | Please enquire. |
| Storage | Aliquot and store at 2°C to 8°C upon receipt. Avoid exposure to light. |
| Dry Ice | No |
| Alias | NCA,CEAL,CD66c,NCA-50/90,Carcinoembryonic antigen-related cell adhesion molecule 6 |
| Background | Antibody anti-CEACAM6 |
| Status | RUO |
Descripción
CEACAM6, also known as CD66c (Cluster of Differentiation 66c), is a member of the carcinoembryonic antigen-related cell adhesion molecules (CEACAMs), which belong to the larger immunoglobulin superfamily (IgSF). CEACAM6 is a glycoprotein primarily involved in intercellular adhesion, immune response modulation, and tumor progression. It is expressed on the surface of various cell types, particularly epithelial cells, granulocytes, and certain cancer cells. CEACAM6, like other CEACAM family members, plays a key role in cellular interactions and communication. In addition to its normal physiological roles in cell adhesion, CEACAM6 is implicated in tumorigenesis, especially in cancers like colorectal, pancreatic, lung, and breast cancer. CEACAM6 is often overexpressed in these malignancies, contributing to tumor growth, metastasis, and resistance to apoptosis. Its expression in the immune system and epithelial cells also means it has important functions in immune modulation and maintaining the integrity of epithelial barriers.
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