Carcinoembryonic Antigen Related Cell Adhesion Molecule 6 (CEACAM6) Antibody
169€ (20 µg)
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935106861
info@markelab.com
name
Carcinoembryonic Antigen Related Cell Adhesion Molecule 6 (CEACAM6) Antibody
category
Primary Antibodies
provider
Abbexa
reference
abx302343
tested applications
ELISA, IHC, IF/ICC
Description
CEACAM6 Antibody is a Rabbit Polyclonal against CEACAM6.
Documents del producto
Instrucciones
Data sheet
Product specifications
| Category | Primary Antibodies |
| Immunogen Target | Carcinoembryonic Antigen Related Cell Adhesion Molecule 6 (CEACAM6) |
| Host | Rabbit |
| Reactivity | Human |
| Recommended Dilution | IHC: 1/20 - 1/200, IF/ICC: 1/50 - 1/200. Optimal dilutions/concentrations should be determined by the end user. |
| Clonality | Polyclonal |
| Conjugation | Unconjugated |
| Isotype | IgG |
| Purity | > 95% |
| Purification | Purified by Protein G. |
| Size 1 | 20 µg |
| Size 2 | 50 µg |
| Size 3 | 100 µg |
| Size 4 | 200 µg |
| Size 5 | 1 mg |
| Form | Liquid |
| Tested Applications | ELISA, IHC, IF/ICC |
| Buffer | 0.01 M PBS, pH 7.4, 0.03% Proclin-300 and 50% Glycerol. |
| Availability | Shipped within 5-10 working days. |
| Storage | Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles. |
| Dry Ice | No |
| UniProt ID | P40199 |
| Gene ID | 4680 |
| OMIM | 163980 |
| Alias | NCA,CEAL,CD66c,NCA-50/90,Carcinoembryonic antigen-related cell adhesion molecule 6 |
| Background | Antibody anti-CEACAM6 |
| Status | RUO |
Descripción
CEACAM6, also known as CD66c (Cluster of Differentiation 66c), is a member of the carcinoembryonic antigen-related cell adhesion molecules (CEACAMs), which belong to the larger immunoglobulin superfamily (IgSF). CEACAM6 is a glycoprotein primarily involved in intercellular adhesion, immune response modulation, and tumor progression. It is expressed on the surface of various cell types, particularly epithelial cells, granulocytes, and certain cancer cells. CEACAM6, like other CEACAM family members, plays a key role in cellular interactions and communication. In addition to its normal physiological roles in cell adhesion, CEACAM6 is implicated in tumorigenesis, especially in cancers like colorectal, pancreatic, lung, and breast cancer. CEACAM6 is often overexpressed in these malignancies, contributing to tumor growth, metastasis, and resistance to apoptosis. Its expression in the immune system and epithelial cells also means it has important functions in immune modulation and maintaining the integrity of epithelial barriers.
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