CaMKI Antibody
357.5€ (100 µg)
Por favor contáctenos para obtener información detallada sobre el precio y disponibilidad.
Name
CaMKI Antibody
Category
Primary Antibodies
Provider
Abbexa
Reference
abx037467
Tested Applications
ELISA, WB, IHC
Description
Rabbit Polyclonal against the CaMKI protein.
Documentos del producto
Instrucciones
Data sheet
Especificaciones del producto
| Category | Primary Antibodies |
| Immunogen Target | Target: CaMKI Immunogen: A peptide corresponding to the C-terminal region of Human CaMKI protein. |
| Host | Rabbit |
| Reactivity | Human |
| Assay Type | Concentration: Lyophilized form: Not applicable. After reconstitution: 1 mg/ml. |
| Recommended Dilution | ELISA: 1/20000 - 1/80000, WB: 1/500 - 1/2000, IHC: 1/100 - 1/200. Optimal dilutions/concentrations should be determined by the end user. |
| Clonality | Polyclonal |
| Conjugation | Unconjugated |
| Isotype | IgG |
| Observed MW | Observed MW: 40 kDa |
| Purification | Purified by antigen affinity column chromatography. |
| Size 1 | 100 µg |
| Size 2 | 1 mg |
| Form | Lyophilized |
| Tested Applications | ELISA, WB, IHC |
| Buffer | Prior to lyophilization: 1% BSA and 0.02% NaN3. |
| Availability | Shipped within 7-15 working days. |
| Storage | Store at -20 °C. Avoid repeated freeze/thaw cycles. |
| Dry Ice | No |
| NCBI Accession | NM_003656 |
| Alias | OX40,ACT35,CD134,IMD16,TXGP1L,OX40L receptor,TAX transcriptionally-activated glycoprotein 1 receptor |
| Background | Antibody anti-TNFRSF4 |
| Status | RUO |
| Note | THIS PRODUCT IS FOR RESEARCH USE ONLY. NOT FOR USE IN DIAGNOSTIC, THERAPEUTIC OR COSMETIC PROCEDURES. NOT FOR HUMAN OR ANIMAL CONSUMPTION. |
Background
TNFRSF4, commonly known as OX40 (CD134), is a member of the tumor necrosis factor receptor (TNFR) superfamily. It is an important costimulatory molecule expressed on T cells, specifically induced upon T cell activation. TNFRSF4 is known for its involvement in regulating immune responses, especially in T-cell proliferation, survival, and memory formation. As an immune-regulatory receptor, it primarily interacts with its ligand, OX40L (TNFSF4), which is expressed on antigen-presenting cells (APCs), such as dendritic cells, B cells, and macrophages. OX40’s role in immune modulation is significant because it amplifies T-cell responses during both acute infections and in chronic immune responses, such as autoimmune diseases and cancer. By sustaining T-cell activation and enhancing immune memory, OX40 has become a central target in immunotherapy research, especially in the contexts of cancer immunotherapy and autoimmune diseases. Its ability to promote prolonged immune responses also makes it a critical regulator in various immune-related diseases, where modulation of OX40-OX40L interactions can potentially benefit patient outcomes.
Productos relacionados
Tumor Necrosis Factor Receptor Superfamily Member 4 / CD134 (TNFRSF4) Antibody
TNFRSF4 Antibody is a Rabbit Polyclonal antibody against TNFRSF4. The protein encoded by this gene is a member of the TN…
Ver producto
Tumor Necrosis Factor Receptor Superfamily Member 4 / CD134 (TNFRSF4) Antibody
TNFRSF4 Antibody is a Rabbit Polyclonal Antibody against TNFRSF4.…
Ver producto