Calcium/Calmodulin-Dependent Protein Kinase Kinase 2 (CAMKK2) Antibody

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Description
Calcium/Calmodulin-Dependent Protein Kinase Kinase 2 (CAMKK2) Antibody is a Rabbit polyclonal antibody for the detection of Human Calcium/Calmodulin-Dependent Protein Kinase Kinase 2 (CAMKK2).
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Product specifications
Category | Primary Antibodies |
Immunogen Target | Calcium/Calmodulin-Dependent Protein Kinase Kinase 2 (CAMKK2) |
Host | Rabbit |
Reactivity | Human |
Recommended Dilution | Optimal dilutions/concentrations should be determined by the end user. |
Clonality | Polyclonal |
Conjugation | Unconjugated |
Isotype | IgG |
Size 1 | 50 µg |
Size 2 | 100 µg |
Form | Liquid |
Tested Applications | ELISA, WB, IHC |
Buffer | 0.01 M PBS, pH 7.4, 50% glycerol, 0.05% Proclin-300. |
Availability | Shipped within 5-12 working days. |
Storage | Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles. |
Dry Ice | No |
UniProt ID | Q96RR4 |
Gene ID | 10645 |
NCBI Accession | NP_001257414.1 |
Background | Antibody anti-CAMKK2 |
Status | RUO |
Descripción
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CAMKK2 antibody
Calcium/calmodulin-dependent protein kinase belonging to a proposed calcium-triggered signaling cascade involved in a number of cellular processes. Isoform 1, isoform 2 and isoform 3 phosphorylate CAMK1 and CAMK4. Isoform 3 phosphorylates CAMK1D. Isoform 4, isoform 5 and isoform 6 lacking part of the calmodulin-binding domain are inactive. Efficiently phosphorylates 5'-AMP-activated protein kinase(AMPK) trimer, including that consisting of PRKAA1, PRKAB1 and PRKAG1. This phosphorylation is stimulated in response to Ca(2+) signals(By similarity). Seems to be involved in hippocampal activation of CREB1(By similarity). May play a role in neurite growth. Isoform 3 may promote neurite elongation, while isoform 1 may promoter neurite branching.
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