Calcitonin Antibody is a Mouse Monoclonal antibody for hormones and steroids against Calcitonin (a.a. 72-81).
Calcitonin gene-related peptide, (CGRP) is a neuropeptide secreted and stored in the nervous system. In humans, CGRP exists in two forms: CGRP alpha (α-CGRP or CGRP I), a 37-amino acid neuropeptide produced through alternative splicing of the CALCA gene (CALC1) and CGRP beta (β-CGRP or CGRP II), which is encoded by a separate, nearby gene known as CALCB (CALC2). These two forms differ only by three amino acids.N-terminal disulfide bond and an amidated C-terminus and allows CGRP to bind to its receptorCGRP has a protective role in various cardiovascular diseases and its involvement in migraines has also been proven. Additionally, it has been discovered that CGRP serves as a crucial link between the nervous system and the skeletal muscle system. CGRP plays a multifaceted role by promoting osteogenesis, inhibiting bone resorption, facilitating vascular growth, and regulating the immune microenvironment.
El péptido relacionado con el gen de la calcitonina (CGRP) es un neuropéptido secretado y almacenado en el sistema nervioso. En humanos, el CGRP existe en dos formas: CGRP alfa (α-CGRP o CGRP I), un neuropéptido de 37 aminoácidos producido mediante corte y empalme alternativo del gen CALCA (CALC1) y CGRP beta (β-CGRP o CGRP II), que está codificado por un gen cercano e independiente conocido como CALCB (CALC2). Estas dos formas se diferencian sólo por tres aminoácidos. Enlace disulfuro N-terminal y un extremo C amidado que permite que el CGRP se una a su receptor. El CGRP tiene un papel protector en diversas enfermedades cardiovasculares y también se ha demostrado su implicación en las migrañas. Además, se ha descubierto que el CGRP sirve como vínculo crucial entre el sistema nervioso y el sistema del músculo esquelético. El CGRP desempeña un papel multifacético al promover la osteogénesis, inhibir la resorción ósea, facilitar el crecimiento vascular y regular el microambiente inmunológico.
Primary Antibodies
Monoclonal
Calcitonin (CALCA)
Mouse
Unconjugated
Liquid
ELISA
Purified.
Buffer contains NaN3 as a preservative.
1 mg
CALCA
No
Shipped within 10-20 working days.
This product is for research use only.
This product is currently in development. The lead time for this product may be several months. Please contact us at inf...
812.5€ (1 ml)
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