Cadherin-5 (CDH5) Antibody
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Pida mas información
935106861
info@markelab.com
Precio
416€ (200 µl)
Antibody anti-CDH5
proveedor
Abbexareference
abx433702Tested Applications
P-ELISA, IF/ICC, FCMreactivity
Humanstatus
RUOclonality
PolyclonalDescripción
Cadherin-5 (CDH5) Antibody is a Goat Polyclonal antibody against Cadherin-5 (CDH5).
Background
Cadherin-5 (CDH5), also known as VE-cadherin (vascular endothelial cadherin), is a calcium-dependent adhesion protein primarily found in endothelial cells, which line blood and lymphatic vessels. It plays a critical role in maintaining the integrity and permeability of blood vessels by facilitating cell-cell adhesion between endothelial cells. CDH5 is essential for normal vascular development, and disruptions in its expression or function have been linked to various diseases, including cancer, cardiovascular diseases, and inflammatory conditions. As a classical cadherin, CDH5 belongs to a larger family of transmembrane proteins characterized by their cadherin repeats, which enable homophilic (same-type cell) binding and the formation of stable adherens junctions.
Características del producto
category
Primary Antibodies
clonality
Polyclonal
reactivity
Human
immunogen target
Cadherin-5 (CDH5)
host
Goat
conjugation
Unconjugated
tested applications
P-ELISA, IF/ICC, FCM
purification
Purified from goat serum by ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide.
recommended dilution
P-ELISA: 1/128000. Optimal dilutions/concentrations should be determined by the end user.
buffer
Tris saline, pH 7.3, containing 0.02% sodium azide and 0.5% bovine serum albumin.
size 1
200 µl
storage
Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles.
or code
CDH5
dry ice
No
availability
Shipped within 5-10 working days.
alias
Cadherin-5,7B4,CD144,7B4 antigen,Vascular endothelial cadherin,VE-cadherin
NCBI accession
NP_001786.2
note
Concentration: 0.5 mg/ml -
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