C-type Lectin Domain Family 4 Member K (CD207) Antibody (PE)

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Description
C-type Lectin Domain Family 4 Member K (CD207) Antibody (PE) is a PE-conjugated Mouse monoclonal antibody for C-type Lectin Domain Family 4 Member K (CD207).
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Product specifications
Category | Primary Antibodies |
Immunogen Target | C-type Lectin Domain Family 4 Member K (CD207) |
Host | Mouse |
Reactivity | Human, Monkey |
Recommended Dilution | FCM: 10 µl/100 µl whole blood or 106 cells. Optimal dilutions/concentrations should be determined by the end user. |
Clonality | Monoclonal |
Conjugation | PE |
Isotype | IgG1 Lambda |
Clone ID | Q211 |
Purification | Purified by size-exclusion chromatography. |
Size 1 | 100 tests |
Form | Liquid |
Tested Applications | FCM |
Buffer | PBS solution with 15 mM sodium azide. |
Availability | Shipped within 5-12 working days. |
Storage | Store at 2-8°C in the dark. Do not freeze. |
Dry Ice | No |
UniProt ID | Q9UJ71 |
Gene ID | 50489 |
Alias | C-type lectin domain family 4 member K,CLEC4K,Langerin |
Background | Antibody anti-CD207 |
Status | RUO |
Descripción
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C-type Lectin Domain Family 4 Member K (CD207) Antibody
CD207 Antibody is a Rabbit Polyclonal antibody against CD207. The protein encoded by this gene is expressed only in Langerhans cells which are immature dendritic cells of the epidermis and mucosa. It is localized in the Birbeck granules, organelles present in the cytoplasm of Langerhans cells and consisting of superimposed and zippered membranes. It is a C-type lectin with mannose binding specificity, and it has been proposed that mannose binding by this protein leads to internalization of antigen into Birbeck granules and providing access to a nonclassical antigen-processing pathway. Mutations in this gene result in Birbeck granules deficiency or loss of sugar binding activity.
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