C-Type Lectin Domain Family 4 Member K (CD207) Antibody
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Description
C-Type Lectin Domain Family 4 Member K (CD207) Antibody is a Rat Monoclonal antibody for the detection of C-Type Lectin Domain Family 4 Member K (CD207) in Mouse samples.
Documents del producto
Product specifications
| Category | Primary Antibodies |
| Immunogen Target | C-Type Lectin Domain Family 4 Member K (CD207) |
| Host | Rat |
| Reactivity | Mouse |
| Clonality | Monoclonal |
| Conjugation | Unconjugated |
| Isotype | IgG1 Kappa |
| Clone ID | T460 |
| Purity | > 95% |
| Purification | Purified by Protein A/G affinity chromatography. |
| Size 1 | 50 µg |
| Size 2 | 100 µg |
| Form | Liquid |
| Tested Applications | ELISA, FCM |
| Buffer | 0.01 M PBS, pH 7.4. |
| Availability | Shipped within 5-12 working days. |
| Storage | Store at 4 °C if the entire vial will be used within 1 week. Aliquot and store at -20 °C or -80 °C for long-term storage. Avoid repeated freeze-thaw cycles. |
| Dry Ice | No |
| UniProt ID | Q8VBX4 |
| Gene ID | 246278 |
| NCBI Accession | NP_659192.2 |
| Alias | C-type lectin domain family 4 member K,CLEC4K,Langerin |
| Background | Antibody anti-CD207 |
| Status | RUO |
| Note | Concentration: 1 mg/ml - |
Descripción
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C-type Lectin Domain Family 4 Member K (CD207) Antibody
CD207 Antibody is a Rabbit Polyclonal antibody against CD207. The protein encoded by this gene is expressed only in Langerhans cells which are immature dendritic cells of the epidermis and mucosa. It is localized in the Birbeck granules, organelles present in the cytoplasm of Langerhans cells and consisting of superimposed and zippered membranes. It is a C-type lectin with mannose binding specificity, and it has been proposed that mannose binding by this protein leads to internalization of antigen into Birbeck granules and providing access to a nonclassical antigen-processing pathway. Mutations in this gene result in Birbeck granules deficiency or loss of sugar binding activity.
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