C-C Motif Chemokine 5 (CCL5) Antibody
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Description
C-C Motif Chemokine 5 (CCL5) Antibody is a monoclonal Nanobody expressed in CHO cells for the detection of Human CCL5.
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Product specifications
| Category | Primary Antibodies |
| Immunogen Target | C-C Motif Chemokine 5 (CCL5) |
| Host | CHO cells |
| Reactivity | Human |
| Clonality | Monoclonal |
| Conjugation | Unconjugated |
| Isotype | VHH-8His-Cys-tag |
| Clone ID | F583 |
| Purity | > 95% (SDS-PAGE) |
| Purification | Purified by Protein A/G affinity chromatography. |
| Size 1 | 100 µg |
| Size 2 | 1 mg |
| Form | Liquid |
| Tested Applications | ELISA, RIA |
| Buffer | 0.01 M PBS, pH 7.4. |
| Availability | Shipped within 5-12 working days. |
| Storage | Store at 4 °C if the entire vial will be used within 1 week. Aliquot and store at -20 °C or -80 °C for long-term storage. Avoid repeated freeze-thaw cycles. |
| Dry Ice | No |
| UniProt ID | P13501 |
| Gene ID | 6352 |
| NCBI Accession | NP_002976.2 |
| Background | Antibody anti-CCL5 |
| Status | RUO |
| Note | Concentration: 1 mg/ml - |
Descripción
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C-C Motif Chemokine 5 (CCL5) Antibody
CCL5 Antibody is a Rabbit Polyclonal antibody against CCL5. This gene is one of several chemokine genes clustered on the q-arm of chromosome 17. Chemokines form a superfamily of secreted proteins involved in immunoregulatory and inflammatory processes. The superfamily is divided into four subfamilies based on the arrangement of the N-terminal cysteine residues of the mature peptide. This chemokine, a member of the CC subfamily, functions as a chemoattractant for blood monocytes, memory T helper cells and eosinophils. It causes the release of histamine from basophils and activates eosinophils. This cytokine is one of the major HIV-suppressive factors produced by CD8+ cells. It functions as one of the natural ligands for the chemokine receptor chemokine (C-C motif) receptor 5 (CCR5), and it suppresses in vitro replication of the R5 strains of HIV-1, which use CCR5 as a coreceptor. Alternative splicing results in multiple transcript variants that encode different isoforms.
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