C-C Chemokine Receptor Type 5 (CCR5) Antibody

Por favor contáctenos para obtener información detallada sobre el precio y disponibilidad.
Description
C-C Chemokine Receptor Type 5 (CCR5) Antibody is a Human Monoclonal antibody for the detection of C-C Chemokine Receptor Type 5 (CCR5) in Human samples.
Documents del producto
Product specifications
Category | Primary Antibodies |
Immunogen Target | C-C Chemokine Receptor Type 5 (CCR5) |
Host | Human |
Reactivity | Human |
Clonality | Monoclonal |
Conjugation | Unconjugated |
Isotype | IgG4 Kappa |
Clone ID | Z977 |
Purity | > 95% |
Purification | Purified by Protein A/G affinity chromatography. |
Size 1 | 50 µg |
Size 2 | 100 µg |
Form | Liquid |
Tested Applications | FCM |
Buffer | 0.01 M PBS, pH 7.4. |
Availability | Shipped within 5-12 working days. |
Storage | Store at 4 °C if the entire vial will be used within 1 week. Aliquot and store at -20 °C or -80 °C for long-term storage. Avoid repeated freeze-thaw cycles. |
Dry Ice | No |
UniProt ID | P51681 |
Gene ID | 1234 |
NCBI Accession | NP_000570.1 |
Alias | CCR5,CHEMR13,CC CKR5,CKR5,CD195,MIP-1 alpha receptor,chemokine (C-C motif) receptor 5 (gene/pseudogene),C-C motif chemokine receptor 5 (gene/pseudogene),CCR-5,CCCKR5,CMKBR5,IDDM22 |
Background | Antibody anti-CCR5 |
Status | RUO |
Note | Concentration: 1 mg/ml - |
Descripción
Related Products

anti- CCR5 antibody
Receptor for a number of inflammatory CC-chemokines including MIP-1-alpha, MIP-1-beta and RANTES and subsequently transduces a signal by increasing the intracellular calcium ion level. May play a role in the control of granulocytic lineage proliferation or differentiation. Acts as a coreceptor(CD4 being the primary receptor) for HIV-1 R5 isolates. (Microbial infection) Acts as a receptor for human immunodeficiency virus-1/HIV-1.
Ver Producto
C-C Chemokine Receptor Type 5 Phospho-Ser349 (CCR5 pS349) Antibody
Rabbit polyclonal antibody against CCR5 protein. Immunogen region is C-terminal. Specificity is as follows for the reactive species: H:S349.
Ver Producto
C-C Chemokine Receptor Type 5 (CCR5) Antibody
This gene encodes a member of the beta chemokine receptor family, which is predicted to be a seven transmembrane protein similar to G protein-coupled receptors. This protein is expressed by T cells and macrophages, and is known to be an important co-receptor for macrophage-tropic virus, including HIV, to enter host cells. Defective alleles of this gene have been associated with the HIV infection resistance. The ligands of this receptor include monocyte chemoattractant protein 2 (MCP-2), macrophage inflammatory protein 1 alpha (MIP-1 alpha), macrophage inflammatory protein 1 beta (MIP-1 beta) and regulated on activation normal T expressed and secreted protein (RANTES). Expression of this gene was also detected in a promyeloblastic cell line, suggesting that this protein may play a role in granulocyte lineage proliferation and differentiation. This gene is located at the chemokine receptor gene cluster region. Two transcript variants encoding the same protein have been found for this gene.
Ver Producto