Butyrophilin Subfamily 3 Member A2 (BTN3A2) Antibody (Biotin)
169€ (20 µg)
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935106861
info@markelab.com
name
Butyrophilin Subfamily 3 Member A2 (BTN3A2) Antibody (Biotin)
category
Primary Antibodies
provider
Abbexa
reference
abx303224
tested applications
ELISA
Description
BTN3A2 Antibody (Biotin) is a Rabbit Polyclonal against BTN3A2 conjugated to Biotin.
Documents del producto
Instrucciones
Data sheet
Product specifications
| Category | Primary Antibodies |
| Immunogen Target | Butyrophilin Subfamily 3 Member A2 (BTN3A2) |
| Host | Rabbit |
| Reactivity | Human |
| Recommended Dilution | Optimal dilutions/concentrations should be determined by the end user. |
| Clonality | Polyclonal |
| Conjugation | Biotin |
| Isotype | IgG |
| Purity | > 95% |
| Purification | Purified by Protein G. |
| Size 1 | 20 µg |
| Size 2 | 50 µg |
| Size 3 | 100 µg |
| Size 4 | 200 µg |
| Size 5 | 1 mg |
| Form | Liquid |
| Tested Applications | ELISA |
| Buffer | 0.01 M PBS, pH 7.4, 0.03% Proclin-300 and 50% Glycerol. |
| Availability | Shipped within 5-10 working days. |
| Storage | Aliquot and store at -20°C. Avoid exposure to light. Avoid repeated freeze/thaw cycles. |
| Dry Ice | No |
| UniProt ID | P78410 |
| Gene ID | 11118 |
| NCBI Accession | NP_001184175.1, NM_001197246.2 |
| OMIM | 613594 |
| Alias | BTF4,BT3.2,CD277,BTN3.2 |
| Background | Antibody anti-BTN3A2 |
| Status | RUO |
Descripción
Butyrophilin subfamily 3 member A2 (BTN3A2) is a protein belonging to the butyrophilin family, which is part of the immunoglobulin superfamily. BTN3A2 is widely expressed in various tissues and is primarily involved in modulating immune responses, particularly through its interactions with immune cells. It plays a key role in regulating T-cell activation and proliferation by acting as a co-stimulatory or inhibitory molecule in immune signaling pathways. This protein is also implicated in the regulation of γδ T cells, which are critical for tumor surveillance and immune responses at epithelial barriers. BTN3A2 is structurally characterized by extracellular immunoglobulin-like domains, a transmembrane region, and an intracellular signaling domain. Its expression is often upregulated in response to inflammatory stimuli, making it an area of interest in autoimmune disorders and cancer immunotherapy. Recent studies suggest that BTN3A2 may have a role in modulating responses to microbial infections and maintaining immune homeostasis, highlighting its potential as a therapeutic target. Further research is needed to clarify its molecular interactions and pathways, particularly in the context of disease pathogenesis and immune modulation.
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