Brain-Specific Angiogenesis Inhibitor 1-Associated Protein 2 (BAIAP2) Antibody
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Description
Brain-Specific Angiogenesis Inhibitor 1-Associated Protein 2 (BAIAP2) Antibody is a Rabbit polyclonal antibody for the detection of Human Brain-Specific Angiogenesis Inhibitor 1-Associated Protein 2 (BAIAP2).
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Product specifications
| Category | Primary Antibodies |
| Immunogen Target | Brain-Specific Angiogenesis Inhibitor 1-Associated Protein 2 (BAIAP2) |
| Host | Rabbit |
| Reactivity | Human |
| Recommended Dilution | Optimal dilutions/concentrations should be determined by the end user. |
| Clonality | Polyclonal |
| Conjugation | Unconjugated |
| Isotype | IgG |
| Size 1 | 50 µg |
| Size 2 | 100 µg |
| Form | Liquid |
| Tested Applications | ELISA, WB, IHC |
| Buffer | 0.01 M PBS, pH 7.4, 50% glycerol, 0.05% Proclin-300. |
| Availability | Shipped within 5-12 working days. |
| Storage | Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles. |
| Dry Ice | No |
| UniProt ID | Q9UQB8 |
| Gene ID | 10458 |
| NCBI Accession | NP_001138360.1 |
| Background | Antibody anti-BAIAP2 |
| Status | RUO |
Descripción
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The protein encoded by this gene has been identified as a brain-specific angiogenesis inhibitor (BAI1)-binding protein. This adaptor protein links membrane bound G-proteins to cytoplasmic effector proteins. This protein functions as an insulin receptor tyrosine kinase substrate and suggests a role for insulin in the central nervous system. It also associates with a downstream effector of Rho small G proteins, which is associated with the formation of stress fibers and cytokinesis. This protein is involved in lamellipodia and filopodia formation in motile cells and may affect neuronal growth-cone guidance. This protein has also been identified as interacting with the dentatorubral-pallidoluysian atrophy gene, which is associated with an autosomal dominant neurodegenerative disease. Alternative splicing results in multiple transcript variants encoding distinct isoforms.
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