Loading...
Bovine SAA(Serum amyloid A protein) ELISA Kit
proveedor
FineTestreference
EB0015Tested Applications
reactivity
bovinestatus
RUOclonality
Background
SAA proteins, belong to a family of apolipoproteins found in association with high-density lipoprotein (HDL) in plasma. These SAA proteins, consisting of 104 amino acids, are encoded within a closely-related gene family and have remained remarkably conserved throughout the course of vertebrate evolution. Notably, fragments of SAA at their amino-terminal end can aggregate into highly structured, insoluble fibrils that accumulate in what is referred to as "secondary" amyloid diseases. In mice, three acute-phase SAA isoforms have been identified, (SAA1, SAA2, and SAA3). During episodes of inflammation, SAA1 and SAA2 are primarily expressed and induced in the liver, whereas SAA3 sees induction in various distinct tissues. In contrast, humans possess a fourth SAA, known as SAA4, which is constitutively expressed in the liver and is thus categorized as constitutive SAA (C-SAA). It's worth noting that a similar protein, now also referred to as SAA4, has been identified in mice
Background
Las proteínas SAA pertenecen a una familia de apolipoproteínas que se encuentran asociadas con las lipoproteínas de alta densidad (HDL) en el plasma. Estas proteínas SAA, que constan de 104 aminoácidos, están codificadas dentro de una familia de genes estrechamente relacionada y se han conservado notablemente a lo largo de la evolución de los vertebrados. En particular, los fragmentos de SAA en su extremo amino terminal pueden agregarse en fibrillas insolubles altamente estructuradas que se acumulan en lo que se conoce como enfermedades amiloides "secundarias". En ratones, se han identificado tres isoformas de SAA de fase aguda (SAA1, SAA2 y SAA3). Durante los episodios de inflamación, SAA1 y SAA2 se expresan e inducen principalmente en el hígado, mientras que SAA3 se induce en varios tejidos distintos. Por el contrario, los seres humanos poseen un cuarto SAA, conocido como SAA4, que se expresa constitutivamente en el hígado y, por tanto, se clasifica como SAA constitutivo (C-SAA). Vale la pena señalar que se ha identificado en ratones una proteína similar, ahora también conocida como SAA4.
Características del producto
category
ELISA Kits
reactivity
bovine
test range
9.375-600ng/ml
assay type
Sandwich ELISA, Double Antibody
assay data
Quantitative
detection method
Colorimetric
sample type
Serum,Plasma,Tissue homogenates,Other biological fluids
size 1
96T
alias
SAA|Serum Amyloid A
storage
2-8 °C for 6 months
or code
SAA
uniprot id
Quizá le pueda interesar
Human Serum amyloid A-4 protein (SAA4) ELISA Kit
proveedor
Abbexareference
abx250406Tested Applications
ELISAreactivity
Humanstatus
RUOHuman Serum amyloid A-4 protein (SAA4) ELISA Kit is an ELISA Kit for the in vitro quantitative measurement of Human Seru...
562.5€ (96 tests)
Ver másMouse Serum Amyloid A Protein (SAA1) ELISA Kit
proveedor
Abbexareference
abx254545Tested Applications
ELISAreactivity
Mousestatus
RUOMouse Serum Amyloid A Protein (SAA1) ELISA Kit is an ELISA Kit for the in vitro quantitative measurement of Mouse Serum ...
525€ (96 tests)
Ver másAmyloid Fibrils (OC) Antibody (PerCP)
proveedor
Abbexareference
abx448399Tested Applications
ELISA, WB, IHC, IF/ICC, IP, DBreactivity
Humanstatus
RUOclonality
PolyclonalAmyloid Fibrils (OC) Antibody (PerCP) is a Rabbit Polyclonal against Amyloid.
600€ (100 µl)
Ver más