Bone Marrow Stromal Cell Antigen 1 (BST1) Antibody
286€ (100 µl)
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935106861
info@markelab.com
name
Bone Marrow Stromal Cell Antigen 1 (BST1) Antibody
category
Primary Antibodies
provider
Abbexa
reference
abx171429
tested applications
WB, IHC, IF/ICC
Description
Bone Marrow Stromal Cell Antigen 1 (BST1) Antibody is a Mouse Monoclonal antibody against Bone Marrow Stromal Cell Antigen 1 (BST1).
Documents del producto
Instrucciones
Data sheet
Product specifications
| Category | Primary Antibodies |
| Immunogen Target | Bone Marrow Stromal Cell Antigen 1 (BST1) |
| Host | Mouse |
| Reactivity | Human |
| Recommended Dilution | WB: 0.01-2 µg/ml, IHC: 5-20 µg/ml, IF/ICC: 5-20 µg/ml. Optimal dilutions/concentrations should be determined by the end user. |
| Clonality | Monoclonal |
| Conjugation | Unconjugated |
| Isotype | lgG1 |
| Purification | Purified by Protein A and Protein G affinity chromatography. |
| Size 1 | 100 µl |
| Size 2 | 200 µl |
| Size 3 | 1 ml |
| Form | Liquid |
| Tested Applications | WB, IHC, IF/ICC |
| Buffer | 0.01 M PBS, pH 7.4, containing 0.05% Proclin-300, 50% glycerol. |
| Availability | Shipped within 5-7 working days. |
| Storage | Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles. |
| Dry Ice | No |
| Alias | ADP-ribosyl cyclase/cyclic ADP-ribose hydrolase 2,ADP-ribosyl cyclase 2,CD157,Cadpr2,Bone marrow stromal cell antigen 1,Cyclic ADP-ribose hydrolase 2 |
| Background | Antibody anti-BST1 |
| Status | RUO |
Descripción
BST1, also known as bone marrow stromal cell antigen 1 or CD157, is a multifunctional glycoprotein involved in immune signaling, cell adhesion, and calcium signaling. BST1 is part of the ADP-ribosyl cyclase family, which also includes CD38, another NAD-glycohydrolase enzyme involved in immune and calcium signaling. It is encoded by the BST1 gene located on chromosome 4p15 in humans and is predominantly expressed in bone marrow stromal cells, but also in peripheral immune cells, endothelial cells, and various tissues with immune functions. BST1 is also identified as a GPI (glycosylphosphatidylinositol)-anchored protein, which enables it to be tethered to cell membranes, facilitating cell-cell interactions and intracellular signaling. This protein is highly relevant in immunology, given its involvement in cellular processes associated with immune responses and inflammation.
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