Beta-Site APP Cleaving Enzyme 2 (BACE2) Antibody (FITC)
169€ (20 µg)
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935106861
info@markelab.com
name
Beta-Site APP Cleaving Enzyme 2 (BACE2) Antibody (FITC)
category
Primary Antibodies
provider
Abbexa
reference
abx316682
Description
BACE2 Antibody (FITC) is a Rabbit Polyclonal against BACE2 conjugated to FITC.
Documents del producto
Instrucciones
Data sheet
Product specifications
| Category | Primary Antibodies |
| Immunogen Target | Beta-Site APP Cleaving Enzyme 2 (BACE2) |
| Host | Rabbit |
| Reactivity | Human |
| Recommended Dilution | Optimal dilutions/concentrations should be determined by the end user. |
| Clonality | Polyclonal |
| Conjugation | FITC |
| Isotype | IgG |
| Purity | > 95% |
| Purification | Purified by Protein G. |
| Size 1 | 20 µg |
| Size 2 | 50 µg |
| Size 3 | 100 µg |
| Size 4 | 200 µg |
| Size 5 | 1 mg |
| Form | Liquid |
| Buffer | 0.01 M PBS, pH 7.4, 0.03% Proclin-300 and 50% Glycerol. |
| Availability | Shipped within 5-10 working days. |
| Storage | Aliquot and store at -20°C. Avoid exposure to light. Avoid repeated freeze/thaw cycles. |
| Dry Ice | No |
| UniProt ID | Q9Y5Z0 |
| Gene ID | 25825 |
| NCBI Accession | NP_036237.2, NM_012105.4 |
| OMIM | 605668 |
| Background | Antibody anti-BACE2 |
| Status | RUO |
Descripción
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BACE2 antibody
Responsible for the proteolytic processing of the amyloid precursor protein(APP). Cleaves APP, between residues 690 and 691, leading to the generation and extracellular release of beta-cleaved soluble APP, and a corresponding cell-associated C-terminal fragment which is later released by gamma-secretase. It has also been shown that it can cleave APP between residues 671 and 672.
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