Beta-Secretase 2 (BACE2) Antibody
442€ (100 µg)
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935106861
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name
Beta-Secretase 2 (BACE2) Antibody
category
Primary Antibodies
provider
Abbexa
reference
abx461626
tested applications
ELISA, SPR
Description
Beta-Secretase 2 (BACE2) Antibody is a monoclonal Nanobody expressed in CHO cells for the detection of Human BACE2.
Documents del producto
Instrucciones
Data sheet
Product specifications
| Category | Primary Antibodies |
| Immunogen Target | Beta-Secretase 2 (BACE2) |
| Host | CHO cells |
| Reactivity | Human |
| Clonality | Monoclonal |
| Conjugation | Unconjugated |
| Isotype | VHH-8His-Cys-tag |
| Clone ID | J113 |
| Purity | > 95% (SDS-PAGE) |
| Purification | Purified by Protein A/G affinity chromatography. |
| Size 1 | 100 µg |
| Size 2 | 1 mg |
| Form | Liquid |
| Tested Applications | ELISA, SPR |
| Buffer | 0.01 M PBS, pH 7.4. |
| Availability | Shipped within 5-12 working days. |
| Storage | Store at 4 °C if the entire vial will be used within 1 week. Aliquot and store at -20 °C or -80 °C for long-term storage. Avoid repeated freeze-thaw cycles. |
| Dry Ice | No |
| UniProt ID | Q9Y5Z0 |
| Gene ID | 25825 |
| NCBI Accession | NP_036237.2 |
| Background | Antibody anti-BACE2 |
| Status | RUO |
| Note | Concentration: 1 mg/ml - |
Descripción
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BACE2 antibody
Responsible for the proteolytic processing of the amyloid precursor protein(APP). Cleaves APP, between residues 690 and 691, leading to the generation and extracellular release of beta-cleaved soluble APP, and a corresponding cell-associated C-terminal fragment which is later released by gamma-secretase. It has also been shown that it can cleave APP between residues 671 and 672.
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