Beta Arrestin 2 (ARRB2) Antibody
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Description
Beta Arrestin 2 Antibody is a Rabbit Polyclonal against Beta Arrestin 2.
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Product specifications
| Category | Primary Antibodies |
| Immunogen Target | Beta Arrestin 2 (ARRB2) |
| Host | Rabbit |
| Reactivity | Human, Mouse |
| Recommended Dilution | WB: 1/1000 - 1/6000, IHC: 1/50 - 1/500, IF/ICC: 1/50 - 1/500, IP: 1/500 - 1/3000. Optimal dilutions/concentrations should be determined by the end user. |
| Clonality | Polyclonal |
| Conjugation | Unconjugated |
| Isotype | IgG |
| Purity | ≥ 95% (SDS-PAGE) |
| Purification | Purified by immunogen affinity chromatography. |
| Size 1 | 100 µg |
| Form | Liquid |
| Tested Applications | ELISA, WB, IHC, IF/ICC, IP |
| Buffer | PBS, pH 7.3, with 0.02% sodium azide and 50% glycerol. |
| Availability | Shipped within 5-12 working days. |
| Storage | Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles. |
| Dry Ice | No |
| UniProt ID | P32121 |
| Gene ID | 409 |
| OMIM | 107941 |
| Background | Antibody anti-ARRB2 |
| Status | RUO |
| Note | Concentration: 2 mg/ml - Validity: 12 months. |
Descripción
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Arrestin Beta 2 (ARRB2) Antibody
ARRB2 Antibody is a Rabbit Polyclonal antibody against ARRB2. Members of arrestin/beta-arrestin protein family are thought to participate in agonist-mediated desensitization of G-protein-coupled receptors and cause specific dampening of cellular responses to stimuli such as hormones, neurotransmitters, or sensory signals. ARRB2, like arrestin beta 1, was shown to inhibit beta-adrenergic receptor function in vitro. It is expressed at high levels in the central nervous system and may play a role in the regulation of synaptic receptors. Besides the brain, a cDNA for ARRB2 was isolated from thyroid gland, and thus it may also be involved in hormone-specific desensitization of TSH receptors. Multiple alternatively spliced transcript variants encoding different isoforms have been found for this gene.
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