Actin, Cytoplasmic 1 (ACTB) Protein
416€ (50 µg)
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935106861
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name
Actin, Cytoplasmic 1 (ACTB) Protein
category
Proteins and Peptides
provider
Abbexa
reference
abx166379
tested applications
WB, SDS-PAGE
Description
Actin, Cytoplasmic 1 (ACTB) Protein is a recombinant protein expressed in E. coli. Shares sequence homology with: Human, Mouse, Rat, Dog, Pig, Cow, Sheep, Horse, Chicken, Guinea pig.
Documents del producto
Instrucciones
Data sheet
Product specifications
| Category | Proteins and Peptides |
| Immunogen Target | Actin, Cytoplasmic 1 (ACTB) |
| Host | E. coli |
| Assay Type | Activity: Not tested Sequence Fragment: Met1-Phe375 Tag: N-terminal His tag |
| Origin | Human, Mouse, Rat, Guinea pig, Dog, Pig, Cow, Sheep, Horse, Chicken |
| Conjugation | Unconjugated |
| Observed MW | Calculated MW: 43.3 kDa Observed MW (SDS-PAGE): 44 kDa |
| Expression | Recombinant |
| Purity | > 90% |
| Size 1 | 50 µg |
| Size 2 | 100 µg |
| Size 3 | 200 µg |
| Size 4 | 500 µg |
| Size 5 | 1 mg |
| Form | Lyophilized |
| Tested Applications | WB, SDS-PAGE |
| Buffer | Prior to lyophilization: PBS, pH 7.4, containing 0.01% Sarcosyl, 5% Trehalose. |
| Availability | Shipped within 5-7 working days. |
| Storage | Store lyophilized form at 2-8°C for up to 1 month. For longer periods, store lyophilized or liquid at -80°C. Avoid repeated freeze–thaw cycles. |
| Dry Ice | No |
| UniProt ID | P60709, P60710, P60711 |
| Gene ID | 60, 11461, 81822 |
| Alias | BKRNS,BNS,BRWS1,CSMH,DDS1,THC8 |
| Background | Protein ACTB |
| Status | RUO |
| Note | THIS PRODUCT IS FOR RESEARCH USE ONLY. NOT FOR USE IN DIAGNOSTIC, THERAPEUTIC OR COSMETIC PROCEDURES. NOT FOR HUMAN OR ANIMAL CONSUMPTION. To keep the original salt concentration, we recommend reconstituting to the original concentration prior to lyophilization (see Concentration) in ddH2O. If a lower concentration is required, dilute in 10 mM PBS, pH 7.4. If a higher concentration is required, the product can be reconstituted directly in 10 mM PBS, pH 7.4, though please note that this will change the overall salt concentration. The stock concentration should be between 0.1-1.0 mg/ml. Do not vortex. Concentration: Prior to lyophilization: 200 µg/ml |
Descripción
ACTB, also known as beta-actin, is a highly conserved protein that serves as a fundamental component of the cytoskeleton in eukaryotic cells. Beta-actin is involved in various cellular processes, including cell structure, motility, and intracellular transport. Beta-actin forms filamentous structures, along with other actin isoforms, which constitute the cytoskeleton. This dynamic network of filaments provides structural support to the cell and is involved in cell shape determination and mechanical stability, motility and migration. It participates in the formation of cell protrusions such as lamellipodia and filopodia, which are essential for cell movement. Beta-actin also plays a role in cell division, where it is involved in cytokinesis, the process of cell division following nuclear division. Furthermore, beta-actin is involved in intracellular transport processes, serving as a track for myosin motor proteins to transport cargo within the cell. This function is essential for the movement of vesicles, organelles, and other cellular components along the cytoskeleton.
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