BCL2-Related Protein A1 Protein

Este producto es parte de BCL2A1 - BCL2 related protein A1
BCL2-Related Protein A1 Protein
234€ (2 µg)

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Name
BCL2-Related Protein A1 Protein
Category
Proteins and Peptides
Provider
Abbexa
Reference
abx263280
Tested Applications
SDS-PAGE

Description

BCL2A1 is a recombinant protein.

Documentos del producto

Instrucciones
Data sheet
Descargar

Especificaciones del producto

Category
Proteins and Peptides
Immunogen Target
BCL2A1
Assay Type
Activity: Not tested
Conjugation
Unconjugated
Expression
Recombinant
Purity
> 95% (SDS-PAGE)
Size 1
2 µg
Size 2
10 µg
Size 3
100 µg
Form
Liquid
Tested Applications
SDS-PAGE
Availability
Shipped within 5-10 working days.
Dry Ice
No
UniProt ID
Q16548
Alias
ACC-1,ACC-2,ACC1,ACC2,BCL2L5,BFL1,GRS,HBPA1,Bcl-2-like protein 5,Bcl2-L-5
Background
Protein BCL2A1
Status
RUO
Note
THIS PRODUCT IS FOR RESEARCH USE ONLY. NOT FOR USE IN DIAGNOSTIC, THERAPEUTIC OR COSMETIC PROCEDURES. NOT FOR HUMAN OR ANIMAL CONSUMPTION.

Background

BCL2 related protein A1 (BCL2A1) is an anti-apoptotic protein belonging to the Bcl-2 family, which plays a pivotal role in regulating apoptosis by inhibiting mitochondrial cell death pathways BCL2A1 functions by preventing the release of pro-apoptotic factors, such as cytochrome c, from mitochondria, thus blocking the activation of caspases and preventing cell death Its expression is often induced under stress conditions, such as oxidative stress and inflammatory stimuli, to protect cells from apoptosis BCL2A1 has been implicated in various cancers, where its overexpression allows tumor cells to evade apoptosis, promoting tumor survival and metastasis Additionally, BCL2A1 has a role in regulating immune cell function, particularly in maintaining the survival of B cells and T cells under stress Dysregulation of BCL2A1 contributes to immune system dysfunction and resistance to chemotherapy in cancer therapy, making it a potential target for therapeutic interventions aimed at promoting cell death in cancer cells

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