BCL2 Like 2 Protein
234€ (5 µg)
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Name
BCL2 Like 2 Protein
Category
Proteins and Peptides
Provider
Abbexa
Reference
abx261122
Tested Applications
SDS-PAGE
Description
BCL2L2 is a recombinant protein.
Documentos del producto
Instrucciones
Data sheet
Especificaciones del producto
| Category | Proteins and Peptides |
| Immunogen Target | BCL2L2 |
| Assay Type | Activity: Not tested |
| Conjugation | Unconjugated |
| Expression | Recombinant |
| Purity | > 95% (SDS-PAGE and RP-HPLC) |
| Size 1 | 5 µg |
| Size 2 | 20 µg |
| Size 3 | 1 mg |
| Form | Liquid |
| Tested Applications | SDS-PAGE |
| Availability | Shipped within 5-10 working days. |
| Dry Ice | No |
| UniProt ID | Q92843 |
| Alias | Bcl-2-like protein 2,BCLW,BCL-W,PPP1R51,BCL2-L-2,Apoptosis regulator Bcl-W |
| Background | Protein BCL2L2 |
| Status | RUO |
| Note | THIS PRODUCT IS FOR RESEARCH USE ONLY. NOT FOR USE IN DIAGNOSTIC, THERAPEUTIC OR COSMETIC PROCEDURES. NOT FOR HUMAN OR ANIMAL CONSUMPTION. |
Background
BCL2 like 2 (BCL2L2), also known as BCL-W, is another anti-apoptotic protein in the Bcl-2 family, crucial for regulating cell survival by preventing mitochondrial apoptosis BCL2L2 interacts with pro-apoptotic proteins such as Bax and Bak, preventing their activation and the subsequent release of cytochrome c from the mitochondria BCL2L2’s role in inhibiting apoptosis is particularly important in cells that undergo high levels of stress, such as hematopoietic cells and certain neuronal populations Dysregulation of BCL2L2 has been associated with cancer, where its overexpression allows tumor cells to evade apoptosis, contributing to tumor survival, metastasis, and resistance to chemotherapy In addition, BCL2L2 is involved in maintaining tissue homeostasis and immune cell survival, influencing T-cell differentiation and activation Studies have suggested that BCL2L2 could be targeted for therapeutic purposes in both cancer and autoimmune diseases, where modulating cell death pathways can improve patient outcomes
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