Basic Leucine Zipper Transcriptional Factor ATF-Like (BATF) Peptide
Por favor contáctenos para obtener información detallada sobre el precio y disponibilidad.
Description
Basic Leucine Zipper Transcriptional Factor ATF-Like (BATF) Peptide is a synthetic peptide. This peptide is used in the production of
Documents del producto
Product specifications
| Category | Proteins and Peptides |
| Immunogen Target | Basic Leucine Zipper Transcriptional Factor ATF-Like (BATF) |
| Host | Synthetic |
| Assay Type | Activity: Not tested. Sequence Fragment: C-Terminus: C-EVVYSAHAFHQPHVS |
| Recommended Dilution | BL (predicted): 0.5 mg/ml. Optimal dilutions/concentrations should be determined by the end user. |
| Conjugation | Unconjugated |
| Size 1 | 100 µg |
| Form | Lyophilized |
| Tested Applications | P-ELISA |
| Buffer | Prior to lyophilization: Deionized water. |
| Availability | Shipped within 5-10 working days. |
| Storage | Aliquot and store at -20 °C. Avoid repeated freeze/thaw cycles. |
| Dry Ice | No |
| Gene ID | 10538, 53314, 299206 |
| NCBI Accession | NP_006390.1 |
| Background | Protein BATF |
| Status | RUO |
| Note | THIS PRODUCT IS FOR RESEARCH USE ONLY. NOT FOR USE IN DIAGNOSTIC, THERAPEUTIC OR COSMETIC PROCEDURES. NOT FOR HUMAN OR ANIMAL CONSUMPTION. Reconstitute in deionized water. |
Descripción
Related Products
BATF antibody
AP-1 family transcription factor that controls the differentiation of lineage-specific cells in the immune system: specifically mediates the differentiation of T-helper 17 cells(Th17), follicular T-helper cells(TfH), CD8(+) dendritic cells and class-switch recombination(CSR) in B-cells. Acts via the formation of a heterodimer with JUNB that recognizes and binds DNA sequence 5'-TGA[CG]TCA-3'. The BATF-JUNB heterodimer also forms a complex with IRF4(or IRF8) in immune cells, leading to recognition of AICE sequence(5'-TGAnTCA/GAAA-3'), an immune-specific regulatory element, followed by cooperative binding of BATF and IRF4(or IRF8) and activation of genes. Controls differentiation of T-helper cells producing interleukin-17(Th17 cells) by binding to Th17-associated gene promoters: regulates expression of the transcription factor RORC itself and RORC target genes such as IL17(IL17A or IL17B). Also involved in differentiation of follicular T-helper cells(TfH) by directing expression of BCL6 and MAF. In B-cells, involved in class-switch recombination(CSR) by controlling the expression of both AICDA and of germline transcripts of the intervening heavy-chain region and constant heavy-chain region(I(H)-C(H)). Following infection, can participate in CD8(+) dendritic cell differentiation via interaction with IRF4 and IRF8 to mediate cooperative gene activation. Regulates effector CD8(+) T-cell differentiation by regulating expression of SIRT1. Following DNA damage, part of a differentiation checkpoint that limits self-renewal of hematopoietic stem cells(HSCs): up-regulated by STAT3, leading to differentiation of HSCs, thereby restricting self-renewal of HSCs(By similarity).
Ver Producto
Recombinant Human BATF
Ver Producto
Basic Leucine Zipper Transcriptional Factor ATF-Like (BATF) Antibody
Rabbit polyclonal antibody against BATF protein. Immunogen region is N-terminal.
Ver Producto