Basic Leucine Zipper Transcription Factor, ATF-Like 2 (BATF2) Antibody (HRP)

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Description
BATF2 Antibody (HRP) is a Rabbit Polyclonal against BATF2 conjugated to HRP.
Documents del producto
Product specifications
Category | Primary Antibodies |
Immunogen Target | Basic Leucine Zipper Transcription Factor, ATF-Like 2 (BATF2) |
Host | Rabbit |
Reactivity | Human |
Recommended Dilution | Optimal dilutions/concentrations should be determined by the end user. |
Clonality | Polyclonal |
Conjugation | HRP |
Isotype | IgG |
Purity | > 95% |
Purification | Purified by Protein G. |
Size 1 | 20 µg |
Size 2 | 50 µg |
Size 3 | 100 µg |
Size 4 | 200 µg |
Size 5 | 1 mg |
Form | Liquid |
Tested Applications | ELISA |
Buffer | 0.01 M PBS, pH 7.4, 0.03% Proclin-300 and 50% Glycerol. |
Availability | Shipped within 5-10 working days. |
Storage | Aliquot and store at -20°C. Avoid exposure to light. Avoid repeated freeze/thaw cycles. |
Dry Ice | No |
UniProt ID | Q8N1L9 |
Gene ID | 116071 |
NCBI Accession | NP_001287736.1, NM_001300807.1, NP_001287737.1, NM_001300808.1 |
OMIM | 614983 |
Alias | B-ATF-2 |
Background | Antibody anti-BATF2 |
Status | RUO |
Descripción
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AP-1 family transcription factor that controls the differentiation of lineage-specific cells in the immune system. Following infection, participates in the differentiation of CD8(+) thymic conventional dendritic cells in the immune system. Acts via the formation of a heterodimer with JUN family proteins that recognizes and binds DNA sequence 5'-TGA[CG]TCA-3' and regulates expression of target genes(By similarity). Selectively suppresses CYR61/CCN1 transcription and hence blocks the downstream cell proliferation signals produced by CYR61 and inhibits CYR61-induced anchorage-independent growth and invasion in several cancer types, such as breast cancer, malignant glioma and metastatic melanoma. Possibly acts by interfering with AP-1 binding to CYR61 promoter.
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