Baculoviral IAP Repeat-Containing Protein 5 (BIRC5) Antibody

247€ (100 µl)
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935106861
info@markelab.com
name
Baculoviral IAP Repeat-Containing Protein 5 (BIRC5) Antibody
category
Primary Antibodies
provider
Abbexa
reference
abx100296
tested applications
WB, IHC, IF/ICC
Description
Monoclonal Antibody to Survivin (BIRC5).
Documents del producto
Instrucciones
Data sheet
Product specifications
Category | Primary Antibodies |
Immunogen Target | Baculoviral IAP Repeat-Containing Protein 5 (BIRC5) |
Host | Mouse |
Reactivity | Human |
Recommended Dilution | WB: 0.01-2 µg/ml, IHC: 5-20 µg/ml, IF/ICC: 5-20 µg/ml. Optimal dilutions/concentrations should be determined by the end user. |
Clonality | Monoclonal |
Conjugation | Unconjugated |
Isotype | IgG2b Kappa |
Purification | Purified by Protein A and Protein G affinity chromatography. |
Size 1 | 100 µl |
Size 2 | 200 µl |
Size 3 | 1 ml |
Form | Liquid |
Tested Applications | WB, IHC, IF/ICC |
Buffer | 0.01 M PBS, pH 7.4, containing 0.05% Proclin-300, 50% glycerol. |
Availability | Shipped within 5-7 working days. |
Storage | Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles. |
Dry Ice | No |
UniProt ID | O15392 |
Background | Antibody anti-BIRC5 |
Status | RUO |
Descripción
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This gene is a member of the inhibitor of apoptosis (IAP) gene family, which encode negative regulatory proteins that prevent apoptotic cell death. IAP family members usually contain multiple baculovirus IAP repeat (BIR) domains, but this gene encodes proteins with only a single BIR domain. The encoded proteins also lack a C-terminus RING finger domain. Gene expression is high during fetal development and in most tumors, yet low in adult tissues. Alternatively spliced transcript variants encoding distinct isoforms have been found for this gene.
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