survivin is an apoptosis inhibitor that is expressed during the G2/M phase of the cell cycle. Associates with the microtubules of the mitotic spindle and any disruption results in the loss of apoptosis activity. May play a role in neoplasia. Inhibitor of caspase-3 and caspase-7. Two splice variant isoforms have been described.
Primary Antibodies
Monoclonal
Human
Baculoviral IAP Repeat-Containing Protein 5 (BIRC5)
Mouse
Unconjugated
Liquid
ELISA, WB, IHC, IF/ICC, FCM
Purified from ascites by Protein G chromatography.
PBS, containing 0.05% sodium azide.
100 µl
Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles.
BIRC5
No
Shipped within 5-10 working days.
This product is for research use only.
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