Baculoviral IAP Repeat-Containing Protein 2 (BIRC2) Antibody
195€ (20 µl)
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935106861
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name
Baculoviral IAP Repeat-Containing Protein 2 (BIRC2) Antibody
category
Primary Antibodies
provider
Abbexa
reference
abx000938
tested applications
ELISA, WB
Description
BIRC2 Antibody is a Rabbit Polyclonal antibody against BIRC2. The protein encoded by this gene is a member of a family of proteins that inhibits apoptosis by binding to tumor necrosis factor receptor-associated factors TRAF1 and TRAF2, probably by interfering with activation of ICE-like proteases. This encoded protein inhibits apoptosis induced by serum deprivation and menadione, a potent inducer of free radicals. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.
Documents del producto
Instrucciones
Data sheet
Product specifications
| Category | Primary Antibodies |
| Immunogen Target | Baculoviral IAP Repeat-Containing Protein 2 (BIRC2) |
| Host | Rabbit |
| Reactivity | Human, Mouse |
| Recommended Dilution | ELISA: 1 µg/ml, WB: 1/500 - 1/2000. Optimal dilutions/concentrations should be determined by the end user. |
| Clonality | Polyclonal |
| Conjugation | Unconjugated |
| Isotype | IgG |
| Purification | Purified by affinity chromatography. |
| Size 1 | 20 µl |
| Size 2 | 100 µl |
| Size 3 | 2 × 100 µl |
| Form | Liquid |
| Tested Applications | ELISA, WB |
| Buffer | PBS, pH 7.3, containing 0.02% sodium azide, 50% glycerol. |
| Availability | Shipped within 5-10 working days. |
| Storage | Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles. |
| Dry Ice | No |
| UniProt ID | Q13490 |
| Gene ID | 329 |
| NCBI Accession | NP_001157.1 |
| Background | Antibody anti-BIRC2 |
| Status | RUO |
| Note | Concentration: > 0.2 mg/ml - |
Descripción
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BIRC2(also known as cIAP1) is a member of the inhibitor of apoptosis protein(IAP) family. The inhibitor of apoptosis(IAP) proteins are a family of anti-apoptotic regulators found in viruses and metazoans. BIRC2 is a nuclear shuttling protein, whose subcellular localization is mediated by the CRM1-dependent nuclear export pathway(PMID: 15265700). This cIAP1 antibody can bind both full length(70kd) and cleaved form(60kd) of the protein.
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