B-Cell Receptor CD22 (CD22) Antibody
Por favor contáctenos para obtener información detallada sobre el precio y disponibilidad.
Description
B-Cell Receptor CD22 (CD22) Antibody is a Mouse Monoclonal antibody for the detection of B-Cell Receptor CD22 (CD22) in Human samples.
Documents del producto
Product specifications
| Category | Primary Antibodies |
| Immunogen Target | B-Cell Receptor CD22 (CD22) |
| Host | Mouse |
| Reactivity | Human |
| Clonality | Monoclonal |
| Conjugation | Unconjugated |
| Isotype | IgG2a Kappa |
| Clone ID | Z457 |
| Purity | > 95% |
| Purification | Purified by Protein A/G affinity chromatography. |
| Size 1 | 50 µg |
| Size 2 | 100 µg |
| Form | Liquid |
| Tested Applications | FCM |
| Buffer | 0.01 M PBS, pH 7.4. |
| Availability | Shipped within 5-12 working days. |
| Storage | Store at 4 °C if the entire vial will be used within 1 week. Aliquot and store at -20 °C or -80 °C for long-term storage. Avoid repeated freeze-thaw cycles. |
| Dry Ice | No |
| UniProt ID | P20273 |
| Gene ID | 933 |
| NCBI Accession | NP_001172028.1 |
| Alias | SIGLEC2,SIGLEC-2,B-cell receptor CD22,B-lymphocyte cell adhesion molecule,BL-CAM,Sialic acid-binding Ig-like lectin 2,T-cell surface antigen Leu-14 |
| Background | Antibody anti-CD22 |
| Status | RUO |
| Note | Concentration: 1 mg/ml - |
Descripción
Related Products
Human SIGLEC2(Sialic Acid Binding Ig Like Lectin 2) ELISA Kit
Ver Producto
anti- CD22 antibody
Mediates B-cell B-cell interactions. May be involved in the localization of B-cells in lymphoid tissues. Binds sialylated glycoproteins; one of which is CD45. Preferentially binds to alpha-2,6-linked sialic acid. The sialic acid recognition site can be masked by cis interactions with sialic acids on the same cell surface. Upon ligand induced tyrosine phosphorylation in the immune response seems to be involved in regulation of B-cell antigen receptor signaling. Plays a role in positive regulation through interaction with Src family tyrosine kinases and may also act as an inhibitory receptor by recruiting cytoplasmic phosphatases via their SH2 domains that block signal transduction through dephosphorylation of signaling molecules.
Ver Producto