B-Cell Leukemia / Lymphoma 2 BH1 Protein

Este producto es parte de BCL2 - BCL2 apoptosis regulator
Product Graph
234€ (2 µg)

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935106861
info@markelab.com
name
B-Cell Leukemia / Lymphoma 2 BH1 Protein
category
Proteins and Peptides
provider
Abbexa
reference
abx262310
tested applications
SDS-PAGE

Description

Bcl-2 -BH1 is a recombinant protein.

Documents del producto

Instrucciones
Data sheet
Descargar

Product specifications

Category
Proteins and Peptides
Immunogen Target
Bcl-2 BH1
Conjugation
Unconjugated
Expression
Recombinant
Purity
> 95% (SDS-PAGE and RP-HPLC)
Size 1
2 µg
Size 2
10 µg
Size 3
1 mg
Form
Lyophilized 
Tested Applications
SDS-PAGE
Availability
Shipped within 5-10 working days.
Dry Ice
No
UniProt ID
P10415
Alias
Bcl-2,PPP1R50,B-Cell CLL/Lymphoma 2
Background
Protein BCL2
Status
RUO
Note
This product is for research use only.   Not for human consumption, cosmetic, therapeutic or diagnostic use.

Descripción

BCL2 apoptosis regulator (BCL2) is a key anti-apoptotic protein that plays a central role in regulating cell survival by preventing mitochondrial-mediated apoptosis BCL2 functions by inhibiting the release of pro-apoptotic factors, such as cytochrome c, from the mitochondria, thus preventing caspase activation and cell death It is highly expressed in various tissues, particularly in immune cells and neurons, where it protects against apoptosis and supports cell longevity Dysregulation of BCL2 expression has been associated with several diseases, including cancer, where its overexpression allows tumor cells to evade cell death, contributing to tumor progression and resistance to therapy BCL2 is also implicated in neurodegenerative diseases, where its dysfunction can lead to excessive neuronal death BCL2 interacts with other members of the Bcl-2 family, including pro-apoptotic proteins like BAX, to finely tune apoptotic signaling and maintain cellular homeostasis Its role in regulating apoptosis and survival pathways makes BCL2 a critical factor in development, aging, and disease management

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