ATP Binding Cassette Subfamily G Member 8 (ABCG8) Antibody (Biotin)
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935106861
info@markelab.com
Precio
169€ (20 µg)
Antibody anti-ABCG8
proveedor
Abbexareference
abx313873Tested Applications
ELISAreactivity
Humanstatus
RUOclonality
PolyclonalDescripción
ABCG8 Antibody (Biotin) is a Rabbit Polyclonal against ABCG8 conjugated to Biotin.
Background
ABCG8 is a membrane-bound transporter belonging to the ABCG subfamily and works as a heterodimer with ABCG5. Expressed mainly in the liver and intestine, it plays a critical role in regulating sterol transport, particularly in the excretion of cholesterol and plant sterols into bile. ABCG8 helps maintain sterol homeostasis and prevent excess sterol absorption. Mutations in ABCG8 are associated with sitosterolemia, leading to sterol accumulation and increased cardiovascular risk. This transporter is crucial for lipid metabolism and overall sterol balance.
Características del producto
category
Primary Antibodies
clonality
Polyclonal
reactivity
Human
immunogen target
ATP Binding Cassette Subfamily G Member 8 (ABCG8)
host
Rabbit
isotype
IgG
conjugation
Biotin
form
Liquid
tested applications
ELISA
purity
> 95%
purification
Purified by Protein G.
recommended dilution
Optimal dilutions/concentrations should be determined by the end user.
buffer
0.01 M PBS, pH 7.4, 0.03% Proclin-300 and 50% Glycerol.
size 1
20 µg
size 2
50 µg
size 3
100 µg
size 4
200 µg
size 5
1 mg
storage
Aliquot and store at -20°C. Avoid exposure to light. Avoid repeated freeze/thaw cycles.
or code
ABCG8
dry ice
No
availability
Shipped within 5-10 working days.
alias
GBD4,STSL,STSL1
uniprot id
NCBI accession
NP_071882.1, NM_022437.2
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