ATP Binding Cassette Subfamily G Member 5 (ABCG5) Antibody
260€ (50 µl)
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Name
ATP Binding Cassette Subfamily G Member 5 (ABCG5) Antibody
Category
Primary Antibodies
Provider
Abbexa
Reference
abx210611
Tested Applications
ELISA, IHC
Description
ABCG5 Antibody is a Rabbit Polyclonal against ABCG5.
Documentos del producto
Instrucciones
Data sheet
Especificaciones del producto
| Category | Primary Antibodies |
| Immunogen Target | Target: ATP Binding Cassette Subfamily G Member 5 (ABCG5) Immunogen: Synthetic peptide of human ABCG5. |
| Host | Rabbit |
| Reactivity | Human |
| Recommended Dilution | ELISA: 1/2000 - 1/5000, IHC: 1/25 - 1/100. Optimal dilutions/concentrations should be determined by the end user. |
| Clonality | Polyclonal |
| Conjugation | Unconjugated |
| Isotype | IgG |
| Purification | Antigen Affinity Chromatography. |
| Size 1 | 50 µl |
| Size 2 | 100 µl |
| Form | Liquid |
| Tested Applications | ELISA, IHC |
| Buffer | PBS, pH 7.4, containing 0.05% NaN3 and 40% Glycerol. |
| Availability | Shipped within 5-10 working days. |
| Storage | Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles. |
| Dry Ice | No |
| UniProt ID | Q9H222 |
| Gene ID | 64240 |
| Alias | STSL,STSL2,Sterolin 1 |
| Background | Antibody anti-ABCG5 |
| Status | RUO |
| Note | THIS PRODUCT IS FOR RESEARCH USE ONLY. NOT FOR USE IN DIAGNOSTIC, THERAPEUTIC OR COSMETIC PROCEDURES. NOT FOR HUMAN OR ANIMAL CONSUMPTION. |
Background
ABCG5 is an integral membrane protein and part of the ATP-binding cassette (ABC) transporter family, specifically subfamily G. Expressed primarily in the liver and intestines, ABCG5 works in tandem with ABCG8 to regulate dietary sterol absorption and biliary sterol excretion. It plays a vital role in maintaining cholesterol and plant sterol homeostasis. Mutations in ABCG5 are linked to sitosterolemia, a rare autosomal recessive disorder characterized by hyperabsorption of plant sterols and cholesterol. Its function is essential for reducing sterol accumulation and preventing cardiovascular diseases.
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