Ataxin 2 (ATXN2) Antibody

Por favor contáctenos para obtener información detallada sobre el precio y disponibilidad.
Description
ATXN2 Antibody is a Goat Polyclonal antibody against ATXN2.
Documents del producto
Product specifications
Category | Primary Antibodies |
Immunogen Target | Ataxin 2 (ATXN2) |
Host | Goat |
Reactivity | Human |
Recommended Dilution | P-ELISA: 1/2000, IF/ICC 10 µg/ml, FCM: 10 µg/ml. Optimal dilutions/concentrations should be determined by the end user. |
Clonality | Polyclonal |
Conjugation | Unconjugated |
Isotype | IgG |
Purification | Purified from goat serum by ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide. |
Size 1 | 200 µl |
Form | Liquid |
Tested Applications | P-ELISA, IF/ICC, FCM |
Buffer | Tris saline, pH 7.3, containing 0.02% sodium azide and 0.5% bovine serum albumin. |
Availability | Shipped within 5-10 working days. |
Storage | Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles. |
Dry Ice | No |
Gene ID | 6311, 20239 |
NCBI Accession | NP_002964.3, NP_001297050.1, NP_001297052.1 |
Alias | ATX2,SCA2,TNRC13 |
Background | Antibody anti-ATXN2 |
Status | RUO |
Note | Concentration: 0.5 mg/ml - |
Descripción
Related Products

ATXN2 antibody
This gene belongs to a group of genes that is associated with microsatellite-expansion diseases, a class of neurological and neuromuscular disorders caused by expansion of short stretches of repetitive DNA. The protein encoded by this gene has two globular domains near the N-terminus, one of which contains a clathrin-mediated trans-Golgi signal and an endoplasmic reticulum exit signal. The encoded cytoplasmic protein localizes to the endoplasmic reticulum and plasma membrane, is involved in endocytosis, and modulates mTOR signals, modifying ribosomal translation and mitochondrial function. The N-terminal region of the protein contains a polyglutamine tract of 14-31 residues that can be expanded in the pathogenic state to 32-200 residues. Intermediate length expansions of this tract increase susceptibility to amyotrophic lateral sclerosis, while long expansions of this tract result in spinocerebellar ataxia-2, an autosomal-dominantly inherited, neurodegenerative disorder. Genome-wide association studies indicate that loss-of-function mutations in this gene may be associated with susceptibility to type I diabetes, obesity and hypertension. Alternative splicing results in multiple transcript variants.
Ver Producto
Human Ataxin 2 (ATXN2) ELISA Kit
Human Ataxin 2 (ATXN2) ELISA Kit is an ELISA Kit for the in vitro quantitative measurement of Human Ataxin 2 (ATXN2) concentrations in tissue homogenates, cell lysates and other biological fluids.
Ver Producto
Mouse Ataxin 2 (ATXN2) ELISA Kit
Mouse Ataxin 2 (ATXN2) ELISA Kit is an ELISA Kit for the in vitro quantitative measurement of Mouse Ataxin 2 (ATXN2) concentrations in tissue homogenates, cell lysates and other biological fluids.
Ver Producto