Arylacetamide Deacetylase (AADAC) Antibody

Este producto es parte de AADAC - Arylacetamide Deacetylase
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169€ (20 µg)

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935106861
info@markelab.com
name
Arylacetamide Deacetylase (AADAC) Antibody
category
Primary Antibodies
provider
Abbexa
reference
abx302949
tested applications
ELISA, IHC

Description

AADAC Antibody is a Rabbit Polyclonal against AADAC.

Documents del producto

Instrucciones
Data sheet
Descargar

Product specifications

Category
Primary Antibodies
Immunogen Target
Arylacetamide Deacetylase (AADAC)
Host
Rabbit
Reactivity
Human
Recommended Dilution
IHC: 1/20 - 1/200. Optimal dilutions/concentrations should be determined by the end user.
Clonality
Polyclonal
Conjugation
Unconjugated
Isotype
IgG
Purity
> 95%
Purification
Purified by Protein G.
Size 1
20 µg
Size 2
50 µg
Size 3
100 µg
Size 4
200 µg
Size 5
1 mg
Form
Liquid
Tested Applications
ELISA, IHC
Buffer
0.01 M PBS, pH 7.4, 0.03% Proclin-300 and 50% Glycerol.
Availability
Shipped within 5-10 working days.
Storage
Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles.
Dry Ice
No
UniProt ID
P22760
Gene ID
13
OMIM
600338
Alias
DAC,CES5A1
Background
Antibody anti-AADAC
Status
RUO

Descripción

Arylacetamide deacetylase (AADAC) is an enzyme primarily found in the liver and gastrointestinal tract, encoded by the AADAC gene. Structurally, AADAC belongs to the amidase signature enzyme family, characterized by a conserved catalytic domain involved in amide hydrolysis. Human arylacetamide deacetylase (AADAC) plays a role in drug detoxification or activation. Drug-metabolizing enzymes play roles in the detoxification or activation of drugs and can also cause drug-induced toxicity through the formation of other metabolites. Among the enzymes that metabolize drugs, cytochrome P450. It is responsible for the metabolism of more than 50% of clinical drugs. Other groups known as non-P450 enzymes also play a role in this process. AADAC prefers compounds with relatively small acyl groups. Especially, AADAC prefers compounds with acetyl group. The hydrolytic activities and functional role of AADAC suggest that other members of this protein family may exhibit similar characteristics. The AADAC family comprises five members, including AADAC and four AADAC-like proteins (AADACL1-4). Except for AADACL1, more commonly known as KIAA1363, all other members of the AADACL protein family, AADACL2, AADACL3 and AADACL4, have so far been poorly investigated and cannot be concluded to have any functional role.

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