Arginase 1 (ARG1) Peptide

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195€ (100 µg)

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935106861
info@markelab.com
name
Arginase 1 (ARG1) Peptide
category
Proteins and Peptides
provider
Abbexa
reference
abx615108
tested applications
P-ELISA

Description

Arginase 1 (ARG1) Peptide is a synthetic peptide. This peptide is used in the production of

Documents del producto

Instrucciones
Data sheet
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Product specifications

Category
Proteins and Peptides
Immunogen Target
Arginase 1 (ARG1)
Host
Synthetic
Assay Type
Activity: Not tested.
Sequence Fragment: C-Terminus: C-NHKPETDYLKPPK
Recommended Dilution
BL (predicted): 0.5 mg/ml. Optimal dilutions/concentrations should be determined by the end user.
Conjugation
Unconjugated
Size 1
100 µg
Form
Lyophilized
Tested Applications
P-ELISA
Buffer
Prior to lyophilization: Deionized water.
Availability
Shipped within 5-10 working days.
Storage
Aliquot and store at -20 °C. Avoid repeated freeze/thaw cycles.
Dry Ice
No
UniProt ID
Q61176
Gene ID
11846, 29221
NCBI Accession
NP_058830.2
Background
Protein ARG1
Status
RUO
Note
THIS PRODUCT IS FOR RESEARCH USE ONLY. NOT FOR USE IN DIAGNOSTIC, THERAPEUTIC OR COSMETIC PROCEDURES. NOT FOR HUMAN OR ANIMAL CONSUMPTION.
Reconstitute in deionized water.

Descripción

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Arginase-1(Liver arginase) belongs to the arginase family. ARG1 is a novel immunohistochemical marker of hepatocellular differentiation in fine needle aspiration cytology and a marker of hepatocytes and hepatocellular neoplasms. ARG1 is closely associated with alternative macrophage activation(PMID:12098359) and ARG1 has been shown to protectmotor neurons from trophic factor deprivation and allow sensory neurons to overcome neurite outgrowth inhibition by myelin proteins(PMID: 20071539).It can exsit as a homotrimer(PMID:16141327) and it has 3 isoforms produced by alternative splicing.Defects in ARG1 are the cause of argininemia(ARGIN). Deletion or TNF-mediated restriction of ARG1 unleashes the production of NO by NOS2, which is critical for pathogen control.(PMID:27117406).

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