Arginase 1 (ARG1) Peptide

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175.5€ (100 µg)

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935106861
info@markelab.com
name
Arginase 1 (ARG1) Peptide
category
Proteins and Peptides
provider
Abbexa
reference
abx269694
tested applications
P-ELISA

Description

Arginase 1 (ARG1) Peptide is a synthetic peptide.

Documents del producto

Instrucciones
Data sheet
Descargar

Product specifications

Category
Proteins and Peptides
Immunogen Target
Arginase 1 (ARG1)
Host
Synthetic
Recommended Dilution
BL (predicted): 0.5 mg/ml. Optimal dilutions/concentrations should be determined by the end user.
Conjugation
Unconjugated
Observed MW
Sequence Fragment: C-Terminus: CFGLAREGNHKPID
Size 1
100 µg
Form
Lyophilized Reconstitute in deionized water.
Tested Applications
P-ELISA
Buffer
Prior to lyophilization: Deionized water.
Availability
Shipped within 5-10 working days.
Storage
Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles.
Dry Ice
No
UniProt ID
P05089
Gene ID
383, 11846, 29221
NCBI Accession
NP_000036.2
Background
Protein ARG1
Note
This product is for research use only.   Not for human consumption, cosmetic, therapeutic or diagnostic use.

Descripción

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Arginase-1(Liver arginase) belongs to the arginase family. ARG1 is a novel immunohistochemical marker of hepatocellular differentiation in fine needle aspiration cytology and a marker of hepatocytes and hepatocellular neoplasms. ARG1 is closely associated with alternative macrophage activation(PMID:12098359) and ARG1 has been shown to protectmotor neurons from trophic factor deprivation and allow sensory neurons to overcome neurite outgrowth inhibition by myelin proteins(PMID: 20071539).It can exsit as a homotrimer(PMID:16141327) and it has 3 isoforms produced by alternative splicing.Defects in ARG1 are the cause of argininemia(ARGIN). Deletion or TNF-mediated restriction of ARG1 unleashes the production of NO by NOS2, which is critical for pathogen control.(PMID:27117406).

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