Arf-GAP With GTPase, ANK Repeat And PH Domain Containing Protein 2 (AGAP2) Antibody

Name: Arf-GAP With GTPase, ANK Repeat And PH Domain Containing Protein 2 (AGAP2) Antibody
Brand: Abbexa
SKU: abx230205
Price: 364 EUR
Availability: OnlineOnly

Este producto es parte de AGAP - Arf-GAP with GTPase ANK repeat and PH domain-containing protein

Pida mas información

935106861

info@markelab.com

Precio

364€ (100 µg)

Antibody anti-AGAP2

proveedor

Abbexa

reference

abx230205

Tested Applications

ELISA, WB, IHC, IF/ICC

reactivity

Human, Mouse, Rat

status

RUO

clonality

Polyclonal

Descripción

AGAP2 Antibody is a Rabbit Polyclonal against AGAP2.

Background

AGAP2, also known as PIKE-A, plays a key role in regulating cell survival, growth signaling pathways, and intracellular transport. It interacts with phosphoinositide 3-kinase (PI3K), enhancing PI3K-Akt signaling and promoting anti-apoptotic responses. AGAP2 contains a GTPase domain, ankyrin repeats, and a PH domain, enabling its participation in vesicle trafficking, cytoskeletal dynamics, and endosomal transport. It is expressed in neurons, where it supports synaptic stability and neuronal survival, and is overexpressed in cancers such as glioblastomas, driving tumor growth and resistance to apoptosis. AGAP2’s dual roles in neuronal plasticity and oncogenesis make it a significant target for therapeutic research.

Características del producto

clonality

Polyclonal

reactivity

Human, Mouse, Rat

immunogen target

Arf-GAP With GTPase, ANK Repeat And PH Domain Containing Protein 2 (AGAP2)

host

Rabbit

isotype

IgG

conjugation

Unconjugated

form

Liquid

tested applications

ELISA, WB, IHC, IF/ICC

purity

≥ 95% (SDS-PAGE)

purification

Purified by immunogen affinity chromatography.

recommended dilution

WB: 1/500 - 1/5000, IHC: 1/20 - 1/200, IF/ICC: 1/20 - 1/200, IP: 1/200 - 1/2000. Optimal dilutions/concentrations should be determined by the end user.

buffer

PBS, pH 7.3, with 0.02% sodium azide and 50% glycerol.

size 1

100 µg

storage

Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles.

or code

AGAP2

dry ice

availability

Shipped within 5-12 working days.

alias

CENTG1,GGAP2,PIKE

uniprot id

https://www.uniprot.org/uniprotkb/Q99490

gene id

https://www.ncbi.nlm.nih.gov/gene/116986

note

Concentration: 2 mg/ml - Validity: 12 months.

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anti- AGAP2 antibody

proveedor

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reference

FNab00205

Tested Applications

ELISA, WB, IHC, IF

reactivity

human,mouse,rat

status

RUO

clonality

polyclonal

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