Apolipoprotein L4 (APOL4) Antibody

Este producto es parte de APOL4 - Apolipoprotein L4
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416€ (200 µl)

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935106861
info@markelab.com
name
Apolipoprotein L4 (APOL4) Antibody
category
Primary Antibodies
provider
Abbexa
reference
abx432354
tested applications
P-ELISA, WB, IHC

Description

APOL4 Antibody is a Goat Polyclonal antibody against APOL4.

Documents del producto

Instrucciones
Data sheet
Descargar

Product specifications

Category
Primary Antibodies
Immunogen Target
Apolipoprotein L4 (APOL4)
Host
Goat
Reactivity
Human
Recommended Dilution
P-ELISA: 1/32000. Optimal dilutions/concentrations should be determined by the end user.
Clonality
Polyclonal
Conjugation
Unconjugated
Isotype
IgG
Purification
Purified from goat serum by ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide.
Size 1
200 µl
Form
Liquid
Tested Applications
P-ELISA, WB, IHC
Buffer
Tris saline, pH 7.3, containing 0.02% sodium azide and 0.5% bovine serum albumin.
Availability
Shipped within 5-10 working days.
Storage
Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles.
Dry Ice
No
Gene ID
80832
NCBI Accession
NP_085146.2, NP_663693.1
Alias
APOLIV,Apolipoprotein L-IV,Apolipoprotein L 4,APOL-IV,Apolipoprotein L4
Background
Antibody anti-APOL4
Status
RUO
Note
Concentration: 0.5 mg/ml -

Descripción

Apolipoprotein L4 (APOL4) is a lesser-studied member of the Apolipoprotein L family and is thought to participate in lipid transport, cellular signaling, and immune modulation. APOL4 is expressed in multiple tissues, including the brain, liver, and immune cells, and localizes to intracellular compartments such as the endoplasmic reticulum and lipid membranes. Like other APOL family members, APOL4 is believed to influence cellular lipid homeostasis, lipid transport pathways, and apoptosis regulation. Its expression is regulated by inflammatory cytokines, suggesting a role in innate immunity and responses to cellular stress. Although the specific biological functions of APOL4 remain unclear, studies indicate that it may contribute to processes such as membrane trafficking, lipid metabolism, and host defense mechanisms against pathogens. Dysregulation of APOL4 expression has been observed in various pathological conditions, including cancers and neurodegenerative diseases, implicating its involvement in cellular survival and disease progression. Further research is needed to fully elucidate APOL4’s functional roles and its potential as a biomarker or therapeutic target in lipid metabolism disorders, immune regulation, and cancer biology.

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