Apolipoprotein C-I (APOC1) Antibody
273€ (100 µl)
Por favor contáctenos para obtener información detallada sobre el precio y disponibilidad.
Name
Apolipoprotein C-I (APOC1) Antibody
Category
Primary Antibodies
Provider
Abbexa
Reference
abx171275
Tested Applications
WB, IHC
Description
Apolipoprotein C-I (APOC1) Antibody is a Mouse Monoclonal antibody against Apolipoprotein C-I (APOC1).
Documentos del producto
Instrucciones
Data sheet
Especificaciones del producto
| Category | Primary Antibodies |
| Immunogen Target | Target: Apolipoprotein C-I (APOC1) |
| Host | Mouse |
| Reactivity | Human |
| Recommended Dilution | WB: 0.01-2 µg/ml, IHC: 5-20 µg/ml, IF/ICC (Predicted): 5-20 µg/ml. Optimal dilutions/concentrations should be determined by the end user. |
| Clonality | Monoclonal |
| Conjugation | Unconjugated |
| Purification | Purified by Protein A and Protein G affinity chromatography. |
| Size 1 | 100 µl |
| Size 2 | 200 µl |
| Size 3 | 1 ml |
| Form | Liquid |
| Tested Applications | WB, IHC |
| Buffer | 0.01 M PBS, pH 7.4, containing 0.05% Proclin-300, 50% glycerol. |
| Availability | Shipped within 5-7 working days. |
| Storage | Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles. |
| Dry Ice | No |
| UniProt ID | P02654 |
| Gene ID | 341 |
| OMIM | 107710 |
| Alias | APOC1, Apo-CI, ApoC-I, apo-CIB, apoC-IB, apolipoprotein C1, Apolipoprotein C-I |
| Background | Antibody anti-APOC1 |
| Status | RUO |
| Note | THIS PRODUCT IS FOR RESEARCH USE ONLY. NOT FOR USE IN DIAGNOSTIC, THERAPEUTIC OR COSMETIC PROCEDURES. NOT FOR HUMAN OR ANIMAL CONSUMPTION. |
Background
APOC1 is a small protein mainly associated with high-density lipoproteins (HDL), and to a lesser extent with very-low-density lipoproteins (VLDL) and chylomicrons. It is synthesized primarily in the liver and plays a crucial role in lipid metabolism by modulating the activity of lipoprotein lipase (LPL) and cholesteryl ester transfer protein (CETP). APOC1 inhibits CETP, thereby reducing the transfer of cholesteryl esters from HDL to LDL and VLDL, which promotes HDL cholesterol levels. It also regulates triglyceride metabolism by modulating lipolytic activity, thereby influencing plasma lipid homeostasis. Elevated APOC1 levels have been associated with dyslipidemia, atherosclerosis, and an increased risk of cardiovascular diseases. It may also play a role in inflammatory responses and has been linked to neurodegenerative diseases like Alzheimer’s disease, where it interacts with amyloid-beta peptides. Research indicates APOC1 has a protective role in the reverse cholesterol transport pathway, facilitating cholesterol efflux from peripheral tissues back to the liver. Genetic variations in the APOC1 gene influence plasma lipid profiles and susceptibility to metabolic disorders, including obesity and insulin resistance.
Productos relacionados
Apolipoprotein C-I (APOC1) Antibody
APOC1 Antibody is a Rabbit Polyclonal antibody against APOC1. The protein encoded by this gene is a member of the Apolip…
Ver producto
Dog Apolipoprotein C-I (APOC1) Protein
Dog Apolipoprotein C-I (APOC1) is a recombinant Dog protein expressed in E. coli.…
Ver producto
Human Apolipoprotein C-I (APOC1) Protein
Human Apolipoprotein C-I (APOC1) is a recombinant Human protein expressed in E. coli.…
Ver producto