Apolipoprotein A2 (APOA2) Antibody Pair
1378€ (5 × 96 tests)
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name
Apolipoprotein A2 (APOA2) Antibody Pair
category
Antibody Pairs
provider
Abbexa
reference
abx370690
tested applications
ELISA
Description
Apolipoprotein A2 (APOA2) Antibody Pair for use in Sandwich ELISA assay development.
Documents del producto
Instrucciones
Data sheet
Product specifications
| Category | Antibody Pairs |
| Immunogen Target | Apolipoprotein A2 (APOA2) |
| Reactivity | Human |
| Assay Data | Detection Antibody Biotinilated |
| Assay Type | Sandwich |
| Recommended Dilution | Dilute the Capture Antibody 125-fold with Coating Buffer. Dilute the Biotin-Conjugated Detection Antibody 200-fold with Detection Antibody Diluent. Optimal dilutions/concentrations should be determined by the end user. |
| Size 1 | 5 × 96 tests |
| Size 2 | 10 × 96 tests |
| Form | Standard: Lyophilized--Liquid (Capture Antibody and Detection Antibody) Reconstitute the standard with Standard Diluent. The volume, and therefore standard concentration, should be determined by the end user. |
| Tested Applications | ELISA |
| Buffer | The Capture and Detection Antibody both contain 0.1% sodium azide. |
| Availability | Please enquire. |
| Storage | Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles. |
| Dry Ice | No |
| Alias | APOA2, Apo-AII, ApoA-II, apoAII, Apolipoprotein A2,APO A2,APO-A2,Apolipoprotein A-II |
| Background | Antibody Pair for APOA2 |
| Status | RUO |
| Note | This antibody pair contains ( 5 x 96 det): Detection: 50 µg Capture: 200 µg Standard: 2 µg This product is for research use only. |
Descripción
APOA2 is the second most abundant protein in HDL particles and is involved in stabilizing HDL structure and influencing cholesterol metabolism. It plays a role in modulating HDL remodeling, impacting the balance between cholesterol efflux and lipid delivery. APOA2 has a controversial role in cardiovascular health, with studies showing both pro-atherogenic and anti-atherogenic effects depending on genetic variants and lipid context. Elevated APOA2 levels have been linked to obesity, insulin resistance, and metabolic syndrome, while deficiencies can impair HDL stability and function. APOA2 interacts with enzymes like hepatic lipase and proteins such as CETP (cholesteryl ester transfer protein), which regulate lipid exchange and metabolism. Its dual role in lipid homeostasis and metabolic health highlights its significance in cardiovascular disease and metabolic disorders.
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The predicted MW of ApoA2 is 11 kDa, while the mature form is smaller (7-10 kDa) since the signal peptide was cleaved. In humans, most of circulating apoA2 exist as dimer.
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