Apolipoprotein A1 (APOA1) Antibody Pair

Este producto es parte de APOA1 - Apolipoprotein A1
Apolipoprotein A1 (APOA1) Antibody Pair

Pida mas información

935106861

info@markelab.com

Precio

1131€ (5 × 96 tests)

Antibody Pair for APOA1

proveedor

Abbexa

reference

abx370182

Tested Applications

ELISA

reactivity

Human

status

RUO

clonality

Descripción

Apolipoprotein A1 (APOA1) Antibody Pair for use in Sandwich ELISA assay development.

Background

APOA1 is the primary protein component of high-density lipoprotein (HDL), often referred to as "good cholesterol," where it plays a crucial role in reverse cholesterol transport. APOA1 facilitates the removal of cholesterol from peripheral tissues and delivers it to the liver for excretion via bile, thus protecting against atherosclerosis and cardiovascular disease. APOA1 is also an activator of lecithin-cholesterol acyltransferase (LCAT), an enzyme critical for HDL maturation and cholesterol esterification. Mutations in the APOA1 gene can result in familial HDL deficiency or amyloidosis, leading to cardiovascular dysfunction and systemic deposits of amyloid fibrils. As a key modulator of lipid metabolism, APOA1 is a major therapeutic target for managing dyslipidemia and reducing cardiovascular risk.

Características del producto

category

Antibody Pairs

reactivity

Human

immunogen target

Apolipoprotein A1 (APOA1)

form

Standard: Lyophilized--Liquid (Capture Antibody and Detection Antibody) Reconstitute the standard with Standard Diluent. The volume, and therefore standard concentration, should be determined by the end user.

tested applications

ELISA

size 1

5 × 96 tests

size 2

10 × 96 tests

recommended dilution

Dilute the Capture Antibody 125-fold with Coating Buffer. Dilute the Biotin-Conjugated Detection Antibody 200-fold with Detection Antibody Diluent. Optimal dilutions/concentrations should be determined by the end user.

buffer

The Capture and Detection Antibody both contain 0.1% sodium azide.

storage

Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles.

or code

APOA1

dry ice

No

availability

Shipped within 5-20 working days.

alias

Apo A1,Apo-A1,apo(a), apolipoprotein A1, Apolipoprotein A-I,HPALP2,APOA1,Apolipoprotein AI

uniprot id

https://www.uniprot.org/uniprotkb/P02647

gene id

https://www.ncbi.nlm.nih.gov/gene/335

NCBI accession

NP_000030.1

note

This antibody pair contains ( 5 x 96 det): Detection: 50 µg Capture: 200 µg Standard: 2 µg This product is for research use only.

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