Apolipoprotein A1 (APOA1) Antibody Pair

Este producto es parte de APOA1 - Apolipoprotein A1
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1131€ (5 × 96 tests)

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935106861
info@markelab.com
name
Apolipoprotein A1 (APOA1) Antibody Pair
category
Antibody Pairs
provider
Abbexa
reference
abx370182
tested applications
ELISA

Description

Apolipoprotein A1 (APOA1) Antibody Pair for use in Sandwich ELISA assay development.

Documents del producto

Instrucciones
Data sheet
Descargar

Product specifications

Category
Antibody Pairs
Immunogen Target
Apolipoprotein A1 (APOA1)
Reactivity
Human
Assay Data
Detection Antibody Biotinilated
Assay Type
Sandwich
Recommended Dilution
Dilute the Capture Antibody 125-fold with Coating Buffer.  Dilute the Biotin-Conjugated Detection Antibody 200-fold with Detection Antibody Diluent.  Optimal dilutions/concentrations should be determined by the end user.
Size 1
5 × 96 tests
Size 2
10 × 96 tests
Form
Standard: Lyophilized--Liquid (Capture Antibody and Detection Antibody)

Reconstitute the standard with Standard Diluent. The volume, and therefore standard concentration, should be determined by the end user.
Tested Applications
ELISA
Buffer
The Capture and Detection Antibody both contain 0.1% sodium azide.
Availability
Shipped within 5-20 working days.
Storage
Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles.
Dry Ice
No
UniProt ID
P02647
Gene ID
335
NCBI Accession
NP_000030.1
OMIM
105200
Alias
Apo A1,Apo-A1,apo(a), apolipoprotein A1, Apolipoprotein A-I,HPALP2,APOA1,Apolipoprotein AI
Background
Antibody Pair for APOA1
Status
RUO
Note
This antibody pair contains ( 5 x 96 det):    Detection:  50 µg  Capture:  200 µg  Standard:  2 µg

This product is for research use only.

Descripción

APOA1 is the primary protein component of high-density lipoprotein (HDL), often referred to as "good cholesterol," where it plays a crucial role in reverse cholesterol transport. APOA1 facilitates the removal of cholesterol from peripheral tissues and delivers it to the liver for excretion via bile, thus protecting against atherosclerosis and cardiovascular disease. APOA1 is also an activator of lecithin-cholesterol acyltransferase (LCAT), an enzyme critical for HDL maturation and cholesterol esterification. Mutations in the APOA1 gene can result in familial HDL deficiency or amyloidosis, leading to cardiovascular dysfunction and systemic deposits of amyloid fibrils. As a key modulator of lipid metabolism, APOA1 is a major therapeutic target for managing dyslipidemia and reducing cardiovascular risk.

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