Apolipoprotein A1 (APOA1) Antibody

Este producto es parte de APOA1 - Apolipoprotein A1
Apolipoprotein A1 (APOA1) Antibody

Pida mas información

935106861

info@markelab.com

Precio

416€ (200 µl)

Antibody anti-APOA1

proveedor

Abbexa

reference

abx432335

Tested Applications

P-ELISA, WB, IHC

reactivity

Human

status

RUO

clonality

Polyclonal

Descripción

APOA1 Antibody is a Goat Polyclonal antibody against APOA1.

Background

APOA1 is the primary protein component of high-density lipoprotein (HDL), often referred to as "good cholesterol," where it plays a crucial role in reverse cholesterol transport. APOA1 facilitates the removal of cholesterol from peripheral tissues and delivers it to the liver for excretion via bile, thus protecting against atherosclerosis and cardiovascular disease. APOA1 is also an activator of lecithin-cholesterol acyltransferase (LCAT), an enzyme critical for HDL maturation and cholesterol esterification. Mutations in the APOA1 gene can result in familial HDL deficiency or amyloidosis, leading to cardiovascular dysfunction and systemic deposits of amyloid fibrils. As a key modulator of lipid metabolism, APOA1 is a major therapeutic target for managing dyslipidemia and reducing cardiovascular risk.

Características del producto

category

Primary Antibodies

clonality

Polyclonal

reactivity

Human

immunogen target

Apolipoprotein A1 (APOA1)

host

Goat

isotype

IgG

conjugation

Unconjugated

form

Liquid

tested applications

P-ELISA, WB, IHC

purification

Purified from goat serum by ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide.

recommended dilution

P-ELISA: 1/4000. Optimal dilutions/concentrations should be determined by the end user.

buffer

Tris saline, pH 7.3, containing 0.02% sodium azide and 0.5% bovine serum albumin.

size 1

200 µl

storage

Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles.

or code

APOA1

dry ice

No

availability

Shipped within 5-10 working days.

alias

Apo A1,Apo-A1,apo(a), apolipoprotein A1, Apolipoprotein A-I,HPALP2,APOA1,Apolipoprotein AI

uniprot id

https://www.uniprot.org/uniprotkb/P02647

gene id

https://www.ncbi.nlm.nih.gov/gene/335

NCBI accession

NP_000030.1

note

Concentration: 0.5 mg/ml -

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