Apo AI Protein
2821€ (100 µg)
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name
Apo AI Protein
category
Proteins and Peptides
provider
Abbexa
reference
abx069751
Description
Apo AI Protein is a Protein produced in Hamster. Apolipoprotein AI (Apo AI) Hamster. It is purified lipoproteins from plasma.
Documents del producto
Instrucciones
Data sheet
Product specifications
| Category | Proteins and Peptides |
| Immunogen Target | Apo AI |
| Host | Hamster |
| Origin | Hamster |
| Conjugation | Unconjugated |
| Purification | Purified from Hamster Plasma |
| Size 1 | 100 µg |
| Form | Liquid |
| Buffer | Buffer contains Thimerosal as a preservative. |
| Availability | Shipped within 10-20 working days. |
| Storage | Aliquot and store at -70 °C. Avoid repeated freeze/thaw cycles. |
| Dry Ice | Yes |
| Alias | Apo A1,Apo-A1,apo(a), apolipoprotein A1, Apolipoprotein A-I,HPALP2,APOA1,Apolipoprotein AI |
| Background | Protein APOA1 |
| Status | RUO |
| Note | This product is for research use only. This product is shipped with dry ice. Not for human consumption, cosmetic, therapeutic or diagnostic use. |
Descripción
APOA1 is the primary protein component of high-density lipoprotein (HDL), often referred to as "good cholesterol," where it plays a crucial role in reverse cholesterol transport. APOA1 facilitates the removal of cholesterol from peripheral tissues and delivers it to the liver for excretion via bile, thus protecting against atherosclerosis and cardiovascular disease. APOA1 is also an activator of lecithin-cholesterol acyltransferase (LCAT), an enzyme critical for HDL maturation and cholesterol esterification. Mutations in the APOA1 gene can result in familial HDL deficiency or amyloidosis, leading to cardiovascular dysfunction and systemic deposits of amyloid fibrils. As a key modulator of lipid metabolism, APOA1 is a major therapeutic target for managing dyslipidemia and reducing cardiovascular risk.
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