Antithrombin-III (SERPINC1) Antibody (FITC)

Este producto es parte de SERPINC1 - serpin family C member 1
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169€ (20 µg)

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935106861
info@markelab.com
name
Antithrombin-III (SERPINC1) Antibody (FITC)
category
Primary Antibodies
provider
Abbexa
reference
abx317190

Description

SERPINC1 Antibody (FITC) is a Rabbit Polyclonal against SERPINC1 conjugated to FITC.

Documents del producto

Instrucciones
Data sheet
Descargar

Product specifications

Category
Primary Antibodies
Immunogen Target
Antithrombin-III (SERPINC1)
Host
Rabbit
Reactivity
Human
Recommended Dilution
Optimal dilutions/concentrations should be determined by the end user.
Clonality
Polyclonal
Conjugation
FITC
Isotype
IgG
Purity
> 95%
Purification
Purified by Protein G.
Size 1
20 µg
Size 2
50 µg
Size 3
100 µg
Size 4
200 µg
Size 5
1 mg
Form
Liquid
Buffer
0.01 M PBS, pH 7.4, 0.03% Proclin-300 and 50% Glycerol.
Availability
Shipped within 5-10 working days.
Storage
Aliquot and store at -20°C. Avoid exposure to light. Avoid repeated freeze/thaw cycles.
Dry Ice
No
UniProt ID
P01008
Gene ID
462
OMIM
107300
Alias
AT3,AT3D,ATIII,THPH7,ATIII-R2,ATIII-T1,ATIII-T2,Antithrombin-III,Serpin C1
Background
Antibody anti-SERPINC1
Status
RUO

Descripción

SERPINC1, commonly known as the gene encoding antithrombin (AT), is a critical member of the serine protease inhibitor (serpin) family. Antithrombin is primarily synthesized in the liver and secreted into the bloodstream, where it plays a vital role in regulating blood coagulation. As a serpin, its primary function is to inhibit proteases involved in coagulation, such as thrombin and factor Xa, thereby preventing excessive clot formation. Deficiencies or abnormalities in the SERPINC1 gene are closely associated with thrombotic disorders, as they lead to an increased risk of blood clots due to insufficient antithrombin activity. This deficiency can be inherited or acquired, and it plays a significant role in conditions such as deep vein thrombosis (DVT) and pulmonary embolism (PE).

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