ZBTB7B antibody
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Description
Transcription regulator that acts as a key regulator of lineage commitment of immature T-cell precursors. Necessary and sufficient for commitment of CD4 lineage, while its absence causes CD8 commitment. Development of immature T-cell precursors(thymocytes) to either the CD4 helper or CD8 killer T-cell lineages correlates precisely with their T-cell receptor specificity for major histocompatibility complex class II or class I molecules, respectively. Transcriptional repressor of the collagen COL1A1 and COL1A2 genes. May also function as a repressor of fibronectin and possibly other extracellular matrix genes(By similarity).
Documents del producto
Product specifications
| Category | Primary Antibodies |
| Immunogen Target | zinc finger and BTB domain containing 7B (ZBTB7B) |
| Host | Rabbit |
| Reactivity | Human, Mouse, Rat |
| Recommended Dilution | WB: 1:200-1:2000; IF: 1:10-1:100; IP: 1:200-1:1000 |
| Clonality | polyclonal |
| Conjugation | Unconjugated |
| Isotype | IgG |
| Observed MW | 58 kDa |
| Purity | ≥95% as determined by SDS-PAGE |
| Purification | Immunogen affinity purified |
| Size 1 | 100µg |
| Form | liquid |
| Tested Applications | ELISA, WB, IF, IP |
| Storage | PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20℃ for 12 months(Avoid repeated freeze / thaw cycles.) |
| UniProt ID | O15156 |
| Gene ID | 51043 |
| Alias | Zinc finger and BTB domain-containing protein 7B,Krueppel-related zinc finger protein cKrox (hcKrox),T-helper-inducing POZ/Krueppel-like factor,Zinc finger and BTB domain-containing protein 15,Zinc finger protein 67 homolog (Zfp-67),Zinc finger protein 857B,Zinc finger protein Th-POK,ZBTB7B,ZBTB15,ZFP67,ZNF857B |
| Background | Antibody anti-ZBTB7B |
| Status | RUO |
| Note | Mol. Weight 58 kDa |
Descripción
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